KEGG   ENZYME: 1.1.1.138Help
Entry
EC 1.1.1.138                Enzyme                                 

Name
mannitol 2-dehydrogenase (NADP+);
mannitol 2-dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-mannitol:NADP+ 2-oxidoreductase
Reaction(IUBMB)
D-mannitol + NADP+ = D-fructose + NADPH + H+ [RN:R00870]
Reaction(KEGG)
Substrate
D-mannitol [CPD:C00392];
NADP+ [CPD:C00006]
Product
D-fructose [CPD:C00095];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.138 created 1972
Pathway
Fructose and mannose metabolism
Reference
1  [PMID:14109183]
  Authors
EDMUNDOWICZ JM, WRISTON JC Jr.
  Title
MANNITOL DEHYDROGENASE FROM AGARICUS CAMPESTRIS.
  Journal
J. Biol. Chem. 238 (1963) 3539-41.
Reference
2  [PMID:14320506]
  Authors
STROBEL GA, KOSUGE T.
  Title
POLYOL METABOLISM IN DIPLODIA VITICOLA DESM.
  Journal
Arch. Biochem. Biophys. 109 (1965) 622-6.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-68-3

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