KEGG   ENZYME: 1.1.1.147Help
Entry
EC 1.1.1.147                Enzyme                                 

Name
16alpha-hydroxysteroid dehydrogenase;
16alpha-hydroxy steroid dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase
Reaction(IUBMB)
a 16alpha-hydroxysteroid + NAD(P)+ = a 16-oxosteroid + NAD(P)H + H+ [RN:R03226 R03227]
Reaction(KEGG)
Substrate
16alpha-hydroxysteroid [CPD:C01090];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
16-oxosteroid [CPD:C01986];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.147 created 1972
Reference
1  [PMID:4380686]
  Authors
Meigs RA, Ryan KJ.
  Title
16-alpha-hydroxysteroid dehydrogenase of rat kidney. Purification, assay, and properties.
  Journal
J. Biol. Chem. 241 (1966) 4011-5.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-74-1

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