KEGG   ENZYME: 1.1.1.15Help
Entry
EC 1.1.1.15                 Enzyme                                 

Name
D-iditol 2-dehydrogenase;
D-sorbitol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-iditol:NAD+ 2-oxidoreductase
Reaction(IUBMB)
D-iditol + NAD+ = D-sorbose + NADH + H+ [RN:R02896]
Reaction(KEGG)
Substrate
D-iditol [CPD:C01489];
NAD+ [CPD:C00003]
Product
D-sorbose [CPD:C00764];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also converts xylitol into L-xylulose and L-glucitol into L-fructose.
History
EC 1.1.1.15 created 1961
Pathway
Pentose and glucuronate interconversions
Fructose and mannose metabolism
Metabolic pathways
Reference
1  [PMID:13373783]
  Authors
SHAW DR.
  Title
Polyol dehydrogenases.  3.  Galactitol dehydrogenase and D-iditol dehydrogenase.
  Journal
Biochem. J. 64 (1956) 394-405.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-22-2

DBGET integrated database retrieval system