KEGG   ENZYME: 1.1.1.150Help
Entry
EC 1.1.1.150                Enzyme                                 

Name
21-hydroxysteroid dehydrogenase (NAD+);
21-hydroxysteroid dehydrogenase (NAD+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
21-hydroxysteroid:NAD+ 21-oxidoreductase
Reaction(IUBMB)
pregnan-21-ol + NAD+ = pregnan-21-al + NADH + H+ [RN:R03043]
Reaction(KEGG)
Substrate
pregnan-21-ol [CPD:C00892];
NAD+ [CPD:C00003]
Product
pregnan-21-al [CPD:C00891];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts on a number of 21-hydroxycorticosteroids.
History
EC 1.1.1.150 created 1972
Reference
1  [PMID:14253469]
  Authors
MONDER C, WHITE A.
  Title
THE 21-HYDROXYSTEROID DEHYDROGENASES OF LIVER. A NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE AND TWO NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASES.
  Journal
J. Biol. Chem. 240 (1965) 71-7.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-75-2

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