KEGG   ENZYME: 1.1.1.152Help
Entry
EC 1.1.1.152                Enzyme                                 

Name
3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase;
etiocholanolone 3alpha-dehydrogenase;
etiocholanolone 3alpha-dehydrogenase;
3alpha-hydroxy-5beta-steroid dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase
Reaction(IUBMB)
3alpha-hydroxy-5beta-androstane-17-one + NAD+ = 5beta-androstane-3,17-dione + NADH + H+ [RN:R04309]
Reaction(KEGG)
Substrate
3alpha-hydroxy-5beta-androstane-17-one;
NAD+ [CPD:C00003]
Product
5beta-androstane-3,17-dione [CPD:C03772];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.152 created 1972
Pathway
Steroid hormone biosynthesis
Reference
1  [PMID:5365796]
  Authors
Roe CR, Kaplan NO.
  Title
Purification and substrate specificities of bacterial hydroxysteroid dehydrogenases.
  Journal
Biochemistry. 8 (1969) 5093-103.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-77-4

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