KEGG   ENZYME: 1.1.1.174Help
Entry
EC 1.1.1.174                Enzyme                                 

Name
cyclohexane-1,2-diol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase
Reaction(IUBMB)
trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH + H+ [RN:R03279]
Reaction(KEGG)
R03279;
(other) R03278 R06621
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Substrate
trans-cyclohexane-1,2-diol [CPD:C03739];
NAD+ [CPD:C00003]
Product
2-hydroxycyclohexan-1-one [CPD:C01147];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also oxidizes, more slowly, the cis isomer and 2-hydroxycyclohexanone.
History
EC 1.1.1.174 created 1978
Pathway
Caprolactam degradation
Microbial metabolism in diverse environments
Reference
1  [PMID:856571]
  Authors
Davey JF, Trudgill PW.
  Title
The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species.
  Journal
Eur. J. Biochem. 74 (1977) 115-27.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
62628-27-7

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