KEGG   ENZYME: 1.1.1.186Help
Entry
EC 1.1.1.186                Enzyme                                 

Name
dTDP-galactose 6-dehydrogenase;
thymidine-diphosphate-galactose dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
dTDP-D-galactose:NADP+ 6-oxidoreductase
Reaction(IUBMB)
dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+ [RN:R07150]
Reaction(KEGG)
R07150;
(other) R03826
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Substrate
dTDP-D-galactose [CPD:C02097];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
dTDP-D-galacturonate [CPD:C03034];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.186 created 1984, modified 2002
Reference
1  [PMID:4381717]
  Authors
Katan R, Avigad G.
  Title
NADP dependent oxidation of TDP-glucose by an enzyme system from sugar beets.
  Journal
Biochem. Biophys. Res. Commun. 24 (1966) 18-24.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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