KEGG   ENZYME: 1.1.1.20Help
Entry
EC 1.1.1.20                 Enzyme                                 

Name
glucuronolactone reductase;
GRase;
gulonolactone dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-gulono-1,4-lactone:NADP+ 1-oxidoreductase
Reaction(IUBMB)
L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + NADPH + H+ [RN:R03183]
Reaction(KEGG)
Substrate
L-gulono-1,4-lactone [CPD:C01040];
NADP+ [CPD:C00006]
Product
D-glucurono-3,6-lactone [CPD:C02670];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.20 created 1961
Pathway
Ascorbate and aldarate metabolism
Reference
1
  Authors
Suzuki, K., Mano, Y. and Shimazono, N.
  Title
Conversion of L-gulonolactone to L-ascorbic acid; properties of the microsomal enzyme in rat liver.
  Journal
J. Biochem. (Tokyo) 48 (1960) 313-315.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-30-2

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