KEGG   ENZYME: 1.1.1.200Help
Entry
EC 1.1.1.200                Enzyme                                 

Name
aldose-6-phosphate reductase (NADPH);
aldose 6-phosphate reductase;
NADP+-dependent aldose 6-phosphate reductase;
A6PR;
aldose-6-P reductase;
aldose-6-phosphate reductase;
alditol 6-phosphate:NADP+ 1-oxidoreductase;
aldose-6-phosphate reductase (NADPH)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-aldose-6-phosphate:NADP+ 1-oxidoreductase
Reaction(IUBMB)
D-sorbitol 6-phosphate + NADP+ = D-glucose 6-phosphate + NADPH + H+ [RN:R00834]
Reaction(KEGG)
Substrate
D-sorbitol 6-phosphate [CPD:C01096];
NADP+ [CPD:C00006]
Product
D-glucose 6-phosphate [CPD:C00092];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
In the reverse reaction, acts also on D-galactose 6-phosphate and, more slowly, on D-mannose 6-phosphate and 2-deoxy-D-glucose 6-phosphate.
History
EC 1.1.1.200 created 1984
Orthology
K00085  
aldose-6-phosphate reductase (NADPH2)
Genes
ATH: 
ALY: 
PPER: 
PMUM: 
MDM: 
103445158(S6PDH)
PXB: 
Taxonomy
Reference
1  [PMID:16661614]
  Authors
Negm FB, Loescher WH.
  Title
Characterization and Partial Purification of Aldose-6-phosphate Reductase (Alditol-6-Phosphate:NADP 1-Oxidoreductase) from Apple Leaves.
  Journal
Plant. Physiol. 67 (1981) 139-142.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
76901-04-7

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