KEGG   ENZYME: 1.1.1.203Help
Entry
EC 1.1.1.203                Enzyme                                 

Name
uronate dehydrogenase;
uronate: NAD-oxidoreductase;
uronic acid dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
uronate:NAD+ 1-oxidoreductase
Reaction(IUBMB)
D-galacturonate + NAD+ + H2O = D-galactarate + NADH + H+ [RN:R01981]
Reaction(KEGG)
R01981;
(other) R09447
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Substrate
D-galacturonate [CPD:C00333];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
D-galactarate [CPD:C00879];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also acts on D-glucuronate.
History
EC 1.1.1.203 created 1972 as EC 1.2.1.35, transferred 1984 to EC 1.1.1.203
Reference
1  [PMID:13657147]
  Authors
KILGORE WW, STARR MP.
  Title
Uronate oxidation by phytopathogenic pseudomonads.
  Journal
Nature. 183 (1959) 1412-3.
  Organism
Pseudomonas sp.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-98-9

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