KEGG   ENZYME: 1.1.1.216Help
Entry
EC 1.1.1.216                Enzyme                                 

Name
farnesol dehydrogenase (NADP+);
NADP+-farnesol dehydrogenase;
farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(2E,6E)-farnesol:NADP+ 1-oxidoreductase
Reaction(IUBMB)
(2E,6E)-farnesol + NADP+ = (2E,6E)-farnesal + NADPH + H+ [RN:R03264]
Reaction(KEGG)
Substrate
(2E,6E)-farnesol [CPD:C01126];
NADP+ [CPD:C00006]
Product
(2E,6E)-farnesal [CPD:C03461];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts, more slowly, on (2Z,6E)-farnesol, geraniol, citronerol and nerol.
History
EC 1.1.1.216 created 1989
Pathway
ec00900  Terpenoid backbone biosynthesis
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec00981  Insect hormone biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K15890  NADP+-dependent farnesol dehydrogenase
Genes
DME: Dmel_CG9360
DPO: Dpse_GA10693 Dpse_GA12578 Dpse_GA17238 Dpse_GA21729
DAN: Dana_GF16365 Dana_GF17260 Dana_GF20253
DER: Dere_GG17506 Dere_GG18834
DPE: Dper_GL15228 Dper_GL20303 Dper_GL24037 Dper_GL27161
DSE: Dsec_GM10850 Dsec_GM13047
DSI: Dsimw501_GD15972(Dsim_GD15972) Dsimw501_GD19832(Dsim_GD19832)
DWI: Dwil_GK14222 Dwil_GK14224
DYA: Dyak_GE15260 Dyak_GE17599
DGR: Dgri_GH18905 Dgri_GH24588
AAG: 23687872
AME: 551640(GB12522)
BIM: 100743402
BTER: 100647945
SOC: 105199354
AEC: 105144197
NVI: 100121837
TCA: 658671
NVL: 108565825
PRAP: 110991447
DNX: 107163401
ZNE: 110834649
 » show all
Taxonomy
Reference
1
  Authors
Inoue, H., Tsuji, H. and Uritani, I.
  Title
Characterization and activity change of farnesol dehydrogenase in black rot fungus-infected sweet-potato.
  Journal
Agric. Biol. Chem. 48 (1984) 733-738.
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.216
IUBMB Enzyme Nomenclature: 1.1.1.216
ExPASy - ENZYME nomenclature database: 1.1.1.216
BRENDA, the Enzyme Database: 1.1.1.216
CAS: 89089-75-8 90804-55-0

DBGET integrated database retrieval system