KEGG   ENZYME: 1.1.1.217Help
Entry
EC 1.1.1.217                Enzyme                                 

Name
benzyl-2-methyl-hydroxybutyrate dehydrogenase;
benzyl 2-methyl-3-hydroxybutyrate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase
Reaction(IUBMB)
benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP+ = benzyl 2-methyl-3-oxobutanoate + NADPH + H+ [RN:R04370]
Reaction(KEGG)
Substrate
benzyl (2R,3S)-2-methyl-3-hydroxybutanoate [CPD:C04561];
NADP+ [CPD:C00006]
Product
benzyl 2-methyl-3-oxobutanoate [CPD:C04000];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts on benzyl (2S,3S)-2-methyl-3-hydroxybutanoate; otherwise highly specific.
History
EC 1.1.1.217 created 1989
Reference
1
  Authors
Furuichi, A., Akita, H., Matsukura, H., Oishi, T. and Horikoshi, K.
  Title
Purification and properties of an asymmetric reduction enzyme of 2-methyl-3-oxobutyrate in baker's yeast.
  Journal
Agric. Biol. Chem. 49 (1985) 2563-2570.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
99332-62-4

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