KEGG   ENZYME: 1.1.1.223Help
Entry
EC 1.1.1.223                Enzyme                                 

Name
isopiperitenol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(-)-trans-isopiperitenol:NAD+ oxidoreductase
Reaction(IUBMB)
(-)-trans-isopiperitenol + NAD+ = (-)-isopiperitenone + NADH + H+ [RN:R03261]
Reaction(KEGG)
Substrate
(-)-trans-isopiperitenol [CPD:C01123];
NAD+ [CPD:C00003]
Product
(-)-isopiperitenone [CPD:C02485];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts on (-)-trans-isopiperitenol, (+)-trans-piperitenol and (+)-trans-pulegol. Involved in the biosynthesis of menthol and related monoterpenes in peppermint (Mentha piperita) leaves.
History
EC 1.1.1.223 created 1989
Pathway
ec00902  Monoterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K15090  isopiperitenol dehydrogenase
Reference
1  [PMID:3885858]
  Authors
Kjonaas RB, Venkatachalam KV, Croteau R.
  Title
Metabolism of monoterpenes: oxidation of isopiperitenol to isopiperitenone, and subsequent isomerization to piperitenone by soluble enzyme preparations from peppermint (Mentha piperita) leaves.
  Journal
Arch. Biochem. Biophys. 238 (1985) 49-60.
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.223
IUBMB Enzyme Nomenclature: 1.1.1.223
ExPASy - ENZYME nomenclature database: 1.1.1.223
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.223
BRENDA, the Enzyme Database: 1.1.1.223
CAS: 96595-05-0

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