KEGG   ENZYME: 1.1.1.224Help
Entry
EC 1.1.1.224                Enzyme                                 

Name
mannose-6-phosphate 6-reductase;
NADPH-dependent mannose 6-phosphate reductase;
mannose-6-phosphate reductase;
6-phosphomannose reductase;
NADP+-dependent mannose-6-P:mannitol-1-P oxidoreductase;
NADPH-dependent M6P reductase;
NADPH-mannose-6-P reductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-mannitol-1-phosphate:NADP+ 6-oxidoreductase
Reaction(IUBMB)
D-mannitol 1-phosphate + NADP+ = D-mannose 6-phosphate + NADPH + H+ [RN:R01817]
Reaction(KEGG)
Substrate
D-mannitol 1-phosphate [CPD:C00644];
NADP+ [CPD:C00006]
Product
D-mannose 6-phosphate [CPD:C00275];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Involved in the biosynthesis of mannitol in celery (Apium graveolens) leaves.
History
EC 1.1.1.224 created 1989
Reference
1  [PMID:16663332]
  Authors
Rumpho ME, Edwards GE, Loescher WH.
  Title
A Pathway for Photosynthetic Carbon Flow to Mannitol in Celery Leaves : Activity and Localization of Key Enzymes.
  Journal
Plant. Physiol. 73 (1983) 869-873.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
88747-79-9

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