KEGG   ENZYME: 1.1.1.226Help
Entry
EC 1.1.1.226                Enzyme                                 

Name
4-hydroxycyclohexanecarboxylate dehydrogenase;
trans-4-hydroxycyclohexanecarboxylate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase
Reaction(IUBMB)
trans-4-hydroxycyclohexanecarboxylate + NAD+ = 4-oxocyclohexanecarboxylate + NADH + H+ [RN:R04307]
Reaction(KEGG)
Substrate
trans-4-hydroxycyclohexanecarboxylate [CPD:C04404];
NAD+ [CPD:C00003]
Product
4-oxocyclohexanecarboxylate [CPD:C03767];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme from Corynebacterium cyclohexanicum is highly specific for the trans-4-hydroxy derivative.
History
EC 1.1.1.226 created 1990
Reference
1  [PMID:3292236]
  Authors
Obata H, Uebayasi M, Kaneda T.
  Title
Purification and properties of 4-hydroxycyclohexanecarboxylate dehydrogenase from Corynebacterium cyclohexanicum.
  Journal
Eur. J. Biochem. 174 (1988) 451-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
67272-36-0

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