KEGG   ENZYME: 1.1.1.232Help
Entry
EC 1.1.1.232                Enzyme                                 

Name
15-hydroxyicosatetraenoate dehydrogenase;
15-hydroxyeicosatetraenoate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase
Reaction(IUBMB)
(15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate + NAD(P)+ = 15-oxo-5,8,11-cis-13-trans-icosatetraenoate + NAD(P)H + H+ [RN:R04517 R04518]
Reaction(KEGG)
Substrate
(15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate [CPD:C04742];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
15-oxo-5,8,11-cis-13-trans-icosatetraenoate [CPD:C04577];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.232 created 1992
Pathway
Arachidonic acid metabolism
Reference
1  [PMID:3052453]
  Authors
Sok DE, Kang JB, Shin HD.
  Title
15-Hydroxyeicosatetraenoic acid dehydrogenase activity in microsomal fraction of mouse liver homogenate.
  Journal
Biochem. Biophys. Res. Commun. 156 (1988) 524-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
117910-46-0

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