KEGG   ENZYME: 1.1.1.24Help
Entry
EC 1.1.1.24                 Enzyme                                 
Name
quinate dehydrogenase;
quinic dehydrogenase;
quinate:NAD oxidoreductase;
quinate 5-dehydrogenase;
quinate:NAD+ 5-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-quinate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
L-quinate + NAD+ = 3-dehydroquinate + NADH + H+ [RN:R01872]
Reaction(KEGG)
Substrate
L-quinate [CPD:C00296];
NAD+ [CPD:C00003]
Product
3-dehydroquinate [CPD:C00944];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme is specific for quinate as substrate; phenylpyruvate, phenylalanine, cinnamate and shikimate will not act as substrates. NAD+ cannot be replaced by NADP+.
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Orthology
K09484  
quinate dehydrogenase
Genes
DHA: 
PIC: 
NCR: 
PAN: 
MGR: 
FGR: 
SSL: 
BFU: 
ANI: 
NFI: 
AFM: 
AFUA_1G11590
AOR: 
AOR_1_430074(AO090038000263)
ANG: 
ANI_1_1306034(An03g03710)
AFV: 
AFLA_008020 AFLA_068130
ACT: 
ACLA_024050
PCS: 
Pc13g08380
PNO: 
SNOG_11439
 » show all
Taxonomy
Reference
1
  Authors
Gamborg, O.L.
  Title
Aromatic metabolism in plants. III. Quinate dehydrogenase from mung bean cell suspension cultures.
  Journal
Biochim. Biophys. Acta 128 (1966) 483-491.
Reference
2  [PMID:13208693]
  Authors
MITSUHASHI S, DAVIS BD.
  Title
Aromatic biosynthesis. XIII. Conversion of quinic acid to 5-dehydroquinic acid by quinic dehydrogenase.
  Journal
Biochim. Biophys. Acta. 15 (1954) 268-80.
  Organism
Klebsiella pneumoniae [GN:kpn]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-28-8
DBGET integrated database retrieval system