KEGG   ENZYME: 1.1.1.24Help
Entry
EC 1.1.1.24                 Enzyme                                 

Name
quinate dehydrogenase;
quinic dehydrogenase;
quinate:NAD oxidoreductase;
quinate 5-dehydrogenase;
quinate:NAD+ 5-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-quinate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
L-quinate + NAD+ = 3-dehydroquinate + NADH + H+ [RN:R01872]
Reaction(KEGG)
Substrate
L-quinate [CPD:C00296];
NAD+ [CPD:C00003]
Product
3-dehydroquinate [CPD:C00944];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme is specific for quinate as substrate; phenylpyruvate, phenylalanine, cinnamate and shikimate will not act as substrates. NAD+ cannot be replaced by NADP+.
History
EC 1.1.1.24 created 1961, modified 1976, modified 2004
Pathway
ec00400  Phenylalanine, tyrosine and tryptophan biosynthesis
Orthology
K09484  quinate dehydrogenase
Genes
DHA: DEHA2C03674g
PIC: PICST_30813
CTEN: CANTEDRAFT_91884
CAUR: QG37_07708
NCR: NCU06025(qa-3)
NTE: NEUTE1DRAFT46730(NEUTE1DRAFT_46730)
SMP: SMAC_07403
PAN: PODANSg2393
TTT: THITE_2116892
MTM: MYCTH_2309055
MGR: MGG_07781
MAW: MAC_04533
MAJ: MAA_07943
CMT: CCM_06001
ANI: AN1137.2
ANG: ANI_1_1306034(An03g03710)
PTE: PTT_10795
ZTR: MYCGRDRAFT_84424(qa-3)
 » show all
Taxonomy
Reference
1
  Authors
Gamborg, O.L.
  Title
Aromatic metabolism in plants. III. Quinate dehydrogenase from mung bean cell suspension cultures.
  Journal
Biochim. Biophys. Acta 128 (1966) 483-491.
Reference
2  [PMID:13208693]
  Authors
MITSUHASHI S, DAVIS BD.
  Title
Aromatic biosynthesis. XIII. Conversion of quinic acid to 5-dehydroquinic acid by quinic dehydrogenase.
  Journal
Biochim. Biophys. Acta. 15 (1954) 268-80.
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.24
IUBMB Enzyme Nomenclature: 1.1.1.24
ExPASy - ENZYME nomenclature database: 1.1.1.24
BRENDA, the Enzyme Database: 1.1.1.24
CAS: 9028-28-8

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