KEGG   ENZYME: 1.1.1.240Help
Entry
EC 1.1.1.240                Enzyme                                 

Name
N-acetylhexosamine 1-dehydrogenase;
N-acetylhexosamine dehydrogenase;
N-acetyl-D-hexosamine dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase
Reaction(IUBMB)
N-acetyl-alpha-D-glucosamine + NAD+ = N-acetyl-D-glucosaminate + NADH + H+ [RN:R01202]
Reaction(KEGG)
Substrate
N-acetyl-alpha-D-glucosamine [CPD:C20328];
NAD+ [CPD:C00003]
Product
N-acetyl-D-glucosaminate [CPD:C01133];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also acts on N-acetylgalactosamine and, more slowly, on N-acetylmannosamine. Anomeric specificity was tested with N-acetyl-D-glucosamine, and it was shown that the enzyme is specific for the alpha anomer.
History
EC 1.1.1.240 created 1992
Reference
1
  Authors
Horiuchi, T. and Kurokawa, T.
  Title
Purification and characterization of N-acetyl-D-hexosamine dehydrogenase from Pseudomonas sp no 53.
  Journal
Agric. Biol. Chem. 53 (1989) 1919-1925.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
122785-18-6

DBGET integrated database retrieval system