KEGG   ENZYME: 1.1.1.245Help
Entry
EC 1.1.1.245                Enzyme                                 

Name
cyclohexanol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cyclohexanol:NAD+ oxidoreductase
Reaction(IUBMB)
cyclohexanol + NAD+ = cyclohexanone + NADH + H+ [RN:R02229]
Reaction(KEGG)
Substrate
cyclohexanol [CPD:C00854];
NAD+ [CPD:C00003]
Product
cyclohexanone [CPD:C00414];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also oxidizes some other alicyclic alcohols and diols.
History
EC 1.1.1.245 created 1992
Pathway
Caprolactam degradation
Microbial metabolism in diverse environments
Orthology
K19960  
cyclohexanol dehydrogenase
Reference
1  [PMID:2505723]
  Authors
Dangel W, Tschech A, Fuchs G
  Title
Enzyme reactions involved in anaerobic cyclohexanol metabolism by a denitrifying  Pseudomonas species.
  Journal
Arch. Microbiol. 152 (1989) 271-9.
Reference
2  [PMID:1261]
  Authors
Donoghue NA, Trudgill PW.
  Title
The metabolism of cyclohexanol by Acinetobacter NCIB 9871.
  Journal
Eur. J. Biochem. 60 (1975) 1-7.
Reference
3  [PMID:16346796]
  Authors
Trower MK, Buckland RM, Higgins R, Griffin M.
  Title
Isolation and Characterization of a Cyclohexane-Metabolizing Xanthobacter sp.
  Journal
Appl. Environ. Microbiol. 49 (1985) 1282-1289.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
63951-98-4

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