KEGG   ENZYME: 1.1.1.260Help
Entry
EC 1.1.1.260                Enzyme                                 

Name
sulcatone reductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
sulcatol:NAD+ oxidoreductase
Reaction(IUBMB)
sulcatol + NAD+ = sulcatone + NADH + H+ [RN:R05678]
Reaction(KEGG)
Substrate
sulcatol [CPD:C07288];
NAD+ [CPD:C00003]
Product
sulcatone [CPD:C07287];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Studies on the effects of growth-stage and nutrient supply on the stereochemistry of sulcatone reduction in Clostridia pasteurianum, C. tyrobutyricum and Lactobacillus brevis suggest that there may be at least two sulcatone reductases with different stereospecificities.
History
EC 1.1.1.260 created 2000, modified 2001
Reference
1
  Authors
Belan, A., Botle, J., Fauve, A., Gourcy, J.G. and Veschambre, H.
  Title
Use of biological systems for the preparation of chiral molecules. 3. An application in pheromone synthesis: Preparation of sulcatol enantiomers.
  Journal
J. Org. Chem. 52 (1987) 256-260.
Reference
2
  Authors
Tidswell, E.C., Salter, G.J., Kell, D.B. and Morris, J.G.
  Title
Enantioselectivity of sulcatone reduction by some anaerobic bacteria.
  Journal
Enzyme Microb. Technol. 21 (1997) 143-147.
Reference
3
  Authors
Tidswell, E.C., Thompson, A.N. and Morris, J.G.
  Title
Selection in chemostat culture of a mutant strain of Clostridium tryobutyricum improved in its reduction of ketones.
  Journal
J. Appl. Microbiol. Biotechnol. 35 (1991) 317-322.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
196522-54-0

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