KEGG   ENZYME: 1.1.1.265Help
Entry
EC 1.1.1.265                Enzyme                                 

Name
3-methylbutanal reductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
3-methylbutanol:NAD(P)+ oxidoreductase
Reaction(IUBMB)
3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+ [RN:R05685 R05686]
Reaction(KEGG)
Substrate
3-methylbutanol [CPD:C07328];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
3-methylbutanal [CPD:C07329];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme purified from Saccharomyces cerevisiae catalyses the reduction of a number of straight-chain and branched aldehydes, as well as some aromatic aldehydes.
History
EC 1.1.1.265 created 2000
Reference
1  [PMID:9327572]
  Authors
van Iersel MF, Eppink MH, van Berkel WJ, Rombouts FM, Abee T.
  Title
Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from Saccharomyces cerevisiae.
  Journal
Appl. Environ. Microbiol. 63 (1997) 4079-82.
Reference
2
  Authors
Ven Nedervelde, L., Verlinden, V., Philipp, D. and Debourg, A.
  Title
Purification and characterization of yeast 3-methyl butanal reductases involved in the removal of wort carbonyls during fermentation.
  Journal
Proc. 26th Congr.-Eur. Brew. Conv. (1997) 447-454.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
214265-44-8

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