KEGG   ENZYME: 1.1.1.276Help
Entry
EC 1.1.1.276                Enzyme                                 

Name
serine 3-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-serine:NADP+ 3-oxidoreductase
Reaction(IUBMB)
L-serine + NADP+ = 2-ammoniomalonate semialdehyde + NADPH + H+ [RN:R06126]
Reaction(KEGG)
Substrate
L-serine [CPD:C00065];
NADP+ [CPD:C00006]
Product
2-ammoniomalonate semialdehyde [CPD:C11822];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The product 2-ammoniomalonate semialdehyde is spontaneously converted into 2-aminoacetaldehyde and CO2. NAD+ cannot replace NADP+.
History
EC 1.1.1.276 created 2003
Orthology
K05886  
serine 3-dehydrogenase
Genes
XFA: 
XFT: 
PD0114(ydfG)
XFM: 
XFN: 
XFF: 
XCC: 
XCB: 
XCA: 
XCP: 
XCV: 
XAC: 
XCI: 
XAX: 
XAO: 
XOO: 
XOM: 
XOP: 
XOR: 
XAL: 
SML: 
SMT: 
BUJ: 
SMZ: 
PSU: 
PSD: 
HAR: 
ATU: 
Atu4110(sdh)
AGR: 
RIR: 
ZMO: 
ZMN: 
ZMM: 
ZMB: 
ZMI: 
ZMP: 
NPP: 
SPHM: 
SJP: 
SCH: 
AZL: 
ALI: 
AVA: 
CCH: 
 » show all
Taxonomy
Reference
1  [PMID:12092831]
  Authors
Fujisawa H, Nagata S, Chowdhury EK, Matsumoto M, Misono H.
  Title
Cloning and sequencing of the serine dehydrogenase gene from Agrobacterium tumefaciens.
  Journal
Biosci. Biotechnol. Biochem. 66 (2002) 1137-9.
  Sequence
[atu:Atu4110]
Reference
2  [PMID:9028042]
  Authors
Chowdhury EK, Higuchi K, Nagata S, Misono H.
  Title
A novel NADP(+)-dependent serine dehydrogenase from Agrobacterium tumefaciens.
  Journal
Biosci. Biotechnol. Biochem. 61 (1997) 152-7.
  Sequence
[atu:Atu4110]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9038-55-5

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