KEGG   ENZYME: 1.1.1.308Help
Entry
EC 1.1.1.308                Enzyme                                 

Name
sulfopropanediol 3-dehydrogenase;
DHPS 3-dehydrogenase (sulfolactate forming);
2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming);
dihydroxypropanesulfonate 3-dehydrogenase;
hpsN (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(R)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
(R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD+ + H2O = (R)-3-sulfolactate + 2 NADH + 2 H+ [RN:R09545]
Reaction(KEGG)
Substrate
(R)-2,3-dihydroxypropane-1-sulfonate [CPD:C19675];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
(R)-3-sulfolactate [CPD:C11537];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme is involved in degradation of (R)-2,3-dihydroxypropanesulfonate.
History
EC 1.1.1.308 created 2011
Orthology
K15509  
sulfopropanediol 3-dehydrogenase
Genes
ECLO: 
ECLX: 
ECLY: 
EAE: 
EAR: 
LAX: 
VHA: 
VCA: 
VAG: 
VEJ: 
VNI: 
VCY: 
GHO: 
PFS: 
PFE: 
PALK: 
ABK: 
ABAU: 
AMAC: 
AMB: 
GAG: 
GPS: 
SPIU: 
HHU: 
HCO: 
MME: 
TSN: 
REU: 
REH: 
H16_A1694(h16_A1694)
BCN: 
BCH: 
BCM: 
BGP: 
BGO: 
BM43_40(hisD)
BYI: 
BUO: 
BUE: 
BXE: 
BXB: 
DR64_8125(hisD)
BPH: 
PTX: 
BHZ: 
AXY: 
AXYL_01399(hisD2)
AKA: 
AMIM: 
MIM_c09530(hisD2)
VEI: 
ADN: 
ADK: 
RTA: 
Rta_27270(hisD)
LIH: 
DFI: 
DAT: 
HRM2_03140(hisD1)
MLO: 
MES: 
SMD: 
RHI: 
SFH: 
EAD: 
OV14_b0880(hisD1)
ARA: 
REC: 
REI: 
RLE: 
pRL80041(hisD2)
SHZ: 
SNO: 
MNO: 
CHEL: 
RHZ: 
AUA: 
SIL: 
JAN: 
RDE: 
RD1_3808(hisD) RD1_3948(hisD)
RLI: 
PDE: 
PAMI: 
DSH: 
Dshi_2034(hisD2) Dshi_2242(hisD3)
PGA: 
PGA1_c07750(hisD1) PGA1_c25490(hisD2) PGA1_c27370(hisD3)
PGL: 
PGA2_c07530(hisD2) PGA2_c25390(hisD3)
PGD: 
OAT: 
OAR: 
OTM: 
OSB_32490(hpsN)
LMD: 
RED: 
PTP: 
MALG: 
RSU: 
NHU_04453(hisD)
HAT: 
NAR: 
NPP: 
SPHI: 
PUB: 
SAR11_0801(hisD2)
APM: 
APB: 
BCL: 
BMD: 
BMD_1657(hisD)
BMEG: 
BG04_3973(hisD)
BEO: 
VIR: 
SEQO: 
PLN: 
PKU: 
PRT: 
TAE: 
MSM: 
MSG: 
MSB: 
MSN: 
MSH: 
MGO: 
CGT: 
CGS: 
CGG: 
CGY: 
CGLY_10805(hisD1) CGLY_10865(hpsN)
RHA: 
ROP: 
ROP_44710(hisD)
ROA: 
SCB: 
SCX: 
MIM: 
KRA: 
SEN: 
SACE_3119(hisD2)
PSEA: 
PSEE: 
PSEH: 
PSEQ: 
PECQ: 
CWO: 
MRB: 
MRE: 
SACI: 
RSI: 
EOL: 
HDL: 
 » show all
Taxonomy
Reference
1  [PMID:20150239]
  Authors
Mayer J, Huhn T, Habeck M, Denger K, Hollemeyer K, Cook AM
  Title
2,3-Dihydroxypropane-1-sulfonate degraded by Cupriavidus pinatubonensis JMP134: purification of dihydroxypropanesulfonate 3-dehydrogenase.
  Journal
Microbiology. 156 (2010) 1556-64.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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