KEGG   ENZYME: 1.1.1.32Help
Entry
EC 1.1.1.32                 Enzyme                                 

Name
mevaldate reductase;
mevalonic dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(R)-mevalonate:NAD+ oxidoreductase
Reaction(IUBMB)
(R)-mevalonate + NAD+ = mevaldate + NADH + H+ [RN:R02246]
Reaction(KEGG)
Substrate
(R)-mevalonate [CPD:C00418];
NAD+ [CPD:C00003]
Product
mevaldate [CPD:C00772];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.32 created 1961
Reference
1  [PMID:13747804]
  Authors
SCHLESINGER MJ, COON MJ.
  Title
Reduction of mevaldic acid to mevalonic acid by a partially purified enzyme from liver.
  Journal
J. Biol. Chem. 236 (1961) 2421-4.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-33-5

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