KEGG   ENZYME: 1.1.1.347Help
Entry
EC 1.1.1.347                Enzyme                                 

Name
geraniol dehydrogenase (NAD+);
GeDH;
geoA (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
geraniol:NAD+ oxidoreductase
Reaction(IUBMB)
geraniol + NAD+ = geranial + NADH + H+ [RN:R10308]
Reaction(KEGG)
Substrate
geraniol [CPD:C01500];
NAD+ [CPD:C00003]
Product
geranial [CPD:C01499];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme from the bacterium Castellaniella defragrans is most active in vitro with perillyl alcohol [2]. The enzyme from the prune mite Carpoglyphus lactis also acts (more slowly) on farnesol but not on nerol [1].
History
EC 1.1.1.347 created 2013
Pathway
Geraniol degradation
Biosynthesis of antibiotics
Orthology
K19653  
geraniol dehydrogenase (NAD+)
Genes
CDN: 
Taxonomy
Reference
1  [PMID:18422649]
  Authors
Noge K, Kato M, Mori N, Kataoka M, Tanaka C, Yamasue Y, Nishida R, Kuwahara Y
  Title
Geraniol dehydrogenase, the key enzyme in biosynthesis of the alarm pheromone, from the astigmatid mite Carpoglyphus lactis (Acari: Carpoglyphidae).
  Journal
FEBS. J. 275 (2008) 2807-17.
Reference
2  [PMID:22286981]
  Authors
Luddeke F, Wulfing A, Timke M, Germer F, Weber J, Dikfidan A, Rahnfeld T, Linder D, Meyerdierks A, Harder J
  Title
Geraniol and geranial dehydrogenases induced in anaerobic monoterpene degradation by Castellaniella defragrans.
  Journal
Appl. Environ. Microbiol. 78 (2012) 2128-36.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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