KEGG   ENZYME: 1.1.1.366Help
Entry
EC 1.1.1.366                Enzyme                                 

Name
L-idonate 5-dehydrogenase (NAD+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-idonate:NAD+ oxidoreductase
Reaction(IUBMB)
L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+ [RN:R05683]
Reaction(KEGG)
Substrate
L-idonate [CPD:C00770];
NAD+ [CPD:C00003]
Product
5-dehydro-D-gluconate [CPD:C01062];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the catabolism of ascorbate (vitamin C) to tartrate. No activity is observed with NADP+ (cf. EC 1.1.1.264, L-idonate 5-dehydrogenase).
History
EC 1.1.1.366 created 2013
Orthology
K19635  
L-idonate 5-dehydrogenase
Genes
VVI: 
Taxonomy
Reference
1  [PMID:16567629]
  Authors
DeBolt S, Cook DR, Ford CM
  Title
L-tartaric acid synthesis from vitamin C in higher plants.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 5608-13.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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