KEGG   ENZYME: 1.1.1.368Help
Entry
EC 1.1.1.368                Enzyme                                 

Name
6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
6-hydroxycyclohex-1-ene-1-carbonyl-CoA:NAD+ 6-oxidoreductase
Reaction(IUBMB)
6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ = 6-oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+ [RN:R05581]
Reaction(KEGG)
Substrate
6-hydroxycyclohex-1-ene-1-carbonyl-CoA [CPD:C06749];
NAD+ [CPD:C00003]
Product
6-oxocyclohex-1-ene-1-carbonyl-CoA [CPD:C09821];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme participates in the central benzoyl-CoA degradation pathway of some anaerobic bacteria such as Thauera aromatica.
History
EC 1.1.1.368 created 2014
Pathway
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K07538  6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Genes
SHD: SUTH_01655(had)
EBA: ebA5297(had)
AZA: AZKH_2148(had_bzdX)
AZI: AzCIB_1613 AzCIB_4485
TMZ: Tmz1t_2954 Tmz1t_4042
TCL: Tchl_2144
GME: Gmet_2151(bamQ)
GBM: Gbem_1431(bamQ)
GEO: Geob_0097(bamQ)
GEM: GM21_2823
DTO: TOL2_C03830(had)
SAT: SYN_01655
RVA: Rvan_0034
MAG: amb2144
MAGX: XM1_2899
MAGN: WV31_08585
 » show all
Taxonomy
Reference
1  [PMID:10406950]
  Authors
Laempe D, Jahn M, Fuchs G
  Title
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase and 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, enzymes of the benzoyl-CoA pathway  of anaerobic aromatic metabolism in the denitrifying bacterium Thauera aromatica.
  Journal
Eur. J. Biochem. 263 (1999) 420-9.
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.368
IUBMB Enzyme Nomenclature: 1.1.1.368
ExPASy - ENZYME nomenclature database: 1.1.1.368
BRENDA, the Enzyme Database: 1.1.1.368

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