KEGG   ENZYME: 1.1.1.368Help
Entry
EC 1.1.1.368                Enzyme                                 

Name
6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
6-hydroxycyclohex-1-ene-1-carbonyl-CoA:NAD+ 6-oxidoreductase
Reaction(IUBMB)
6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD+ = 6-oxocyclohex-1-ene-1-carbonyl-CoA + NADH + H+ [RN:R05581]
Reaction(KEGG)
Substrate
6-hydroxycyclohex-1-ene-1-carbonyl-CoA [CPD:C06749];
NAD+ [CPD:C00003]
Product
6-oxocyclohex-1-ene-1-carbonyl-CoA [CPD:C09821];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme participates in the central benzoyl-CoA degradation pathway of some anaerobic bacteria such as Thauera aromatica.
History
EC 1.1.1.368 created 2014
Pathway
Benzoate degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K07538  
6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Genes
EBA: 
ebA5297(had)
TMZ: 
GME: 
Gmet_2151(bamQ)
GBM: 
Gbem_1431(bamQ)
GEO: 
Geob_0097(bamQ)
GEM: 
DTO: 
SAT: 
DTI: 
RVA: 
MAG: 
 » show all
Taxonomy
Reference
1  [PMID:10406950]
  Authors
Laempe D, Jahn M, Fuchs G
  Title
6-Hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase and 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase, enzymes of the benzoyl-CoA pathway  of anaerobic aromatic metabolism in the denitrifying bacterium Thauera aromatica.
  Journal
Eur. J. Biochem. 263 (1999) 420-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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