KEGG   ENZYME: 1.1.1.374Help
Entry
EC 1.1.1.374                Enzyme                                 

Name
UDP-N-acetylglucosamine 3-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
UDP-N-acetyl-alpha-D-glucosamine:NAD+ 3-oxidoreductase
Reaction(IUBMB)
UDP-N-acetyl-alpha-D-glucosamine + NAD+ = UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + NADH + H+ [RN:R10785]
Reaction(KEGG)
Substrate
UDP-N-acetyl-alpha-D-glucosamine [CPD:C00043];
NAD+ [CPD:C00003]
Product
UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose [CPD:C20849];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme from the archaeon Methanococcus maripaludis is activated by KCl (200 mM).
History
EC 1.1.1.374 created 2014
Orthology
K18855  
UDP-N-acetylglucosamine 3-dehydrogenase
Genes
MMP: 
MVN: 
MVO: 
MAC: 
MA_4448(idh)
MBA: 
MBY: 
MBW: 
MBAR: 
MMA: 
MMAZ: 
MVC: 
MEK: 
MLS: 
METM: 
MEF: 
MEQ: 
MSJ: 
MSZ: 
MSW: 
MTHE: 
MTHR: 
MHOR: 
MBU: 
MMET: 
MPY: 
MHZ: 
MPD: 
RCI: 
RCIX1923(idhA)
MTH: 
MMG: 
METC: 
MST: 
MSI: 
MRU: 
MEB: 
MMIL: 
MEYE: 
MEL: 
MEW: 
METH: 
MFC: 
MFI: 
MFV: 
MKA: 
PAB: 
PFU: 
PFI: 
TGA: 
TSI: 
TBA: 
THM: 
TLT: 
THS: 
TGY: 
THV: 
ACF: 
HBU: 
PDL: 
PYR: 
THB: 
TCB: 
THF: 
FFO: 
NMR: 
NIR: 
NID: 
NIN: 
CSY: 
NGA: 
NVN: 
NEV: 
TAA: 
CSU: 
NBV: 
TAH: 
KCR: 
AGW: 
 » show all
Taxonomy
Reference
1  [PMID:18634748]
  Authors
Namboori SC, Graham DE
  Title
Enzymatic analysis of uridine diphosphate N-acetyl-D-glucosamine.
  Journal
Anal. Biochem. 381 (2008) 94-100.
  Sequence
[mmp:MMP0352]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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