KEGG   ENZYME: 1.1.1.61Help
Entry
EC 1.1.1.61                 Enzyme                                 
Name
4-hydroxybutyrate dehydrogenase;
gamma-hydroxybutyrate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4-hydroxybutanoate:NAD+ oxidoreductase
Reaction(IUBMB)
4-hydroxybutanoate + NAD+ = succinate semialdehyde + NADH + H+ [RN:R01644]
Reaction(KEGG)
Substrate
4-hydroxybutanoate [CPD:C00989];
NAD+ [CPD:C00003]
Product
succinate semialdehyde [CPD:C00232];
NADH [CPD:C00004];
H+ [CPD:C00080]
Pathway
Butanoate metabolism
Orthology
K00043  
4-hydroxybutyrate dehydrogenase
Genes
RSO: 
RSp0986(gbd2)
REH: 
CTI: 
BMA: 
BMV: 
BML: 
BMN: 
BPS: 
BPM: 
BPL: 
BPD: 
BURPS668_1646 BURPS668_A2018
BPR: 
GBP346_A1691
BPA: 
BPP2084(gbd)
BBR: 
BB1480(gbd)
BME: 
BMEII1094
RDE: 
RD1_2171(gbd)
HNE: 
HNE_0174(gbd)
CPF: 
CPF_0518
CPR: 
CPR_0507
CDF: 
CD630_23380(4hbD)
 » show all
Taxonomy
Reference
1  [PMID:14427301]
  Authors
NIRENBERG MW, JAKOBY WB.
  Title
Enzymatic utilization of gamma-hydroxybutyric acid.
  Journal
J. Biol. Chem. 235 (1960) 954-60.
  Organism
Pseudomonas sp.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-60-8
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