KEGG   ENZYME: 1.1.1.71Help
Entry
EC 1.1.1.71                 Enzyme                                 

Name
alcohol dehydrogenase [NAD(P)+];
retinal reductase (ambiguous);
aldehyde reductase (NADPH/NADH);
alcohol dehydrogenase [NAD(P)]
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
alcohol:NAD(P)+ oxidoreductase
Reaction(IUBMB)
an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+ [RN:R07326 R07328]
Reaction(KEGG)
Substrate
alcohol [CPD:C00069];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
aldehyde [CPD:C00071];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Reduces aliphatic aldehydes of carbon chain length from 2 to 14, with greatest activity on C4, C6 and C8 aldehydes; also reduces retinal to retinol.
History
EC 1.1.1.71 created 1972
Reference
1  [PMID:4300551]
  Authors
Fidge NH, Goodman DS.
  Title
The enzymatic reducation of retinal to retinol in rat intestine.
  Journal
J. Biol. Chem. 243 (1968) 4372-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
37250-10-5

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