KEGG   ENZYME: 1.1.1.82Help
Entry
EC 1.1.1.82                 Enzyme                                 

Name
malate dehydrogenase (NADP+);
NADP+-malic enzyme;
NADP+-malate dehydrogenase;
malic dehydrogenase (nicotinamide adenine dinucleotide phosphate);
malate NADP+ dehydrogenase;
NADP+ malate dehydrogenase;
NADP+-linked malate dehydrogenase;
malate dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(S)-malate:NADP+ oxidoreductase
Reaction(IUBMB)
(S)-malate + NADP+ = oxaloacetate + NADPH + H+ [RN:R00343]
Reaction(KEGG)
Substrate
(S)-malate [CPD:C00149];
NADP+ [CPD:C00006]
Product
oxaloacetate [CPD:C00036];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Activated by light.
History
EC 1.1.1.82 created 1972
Pathway
Pyruvate metabolism
Carbon fixation in photosynthetic organisms
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K00051  
malate dehydrogenase (NADP+)
Genes
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
MTR: 
CAM: 
FVE: 
CSV: 
RCU: 
POP: 
POPTR_0008s03160g(POPTRDRAFT_820232)
VVI: 
SLY: 
543805(mdh)
SOT: 
OSA: 
DOSA: 
Os08t0562100-01(Os08g0562100)
OBR: 
BDI: 
SBI: 
SORBI_07g023920(SORBIDRAFT_07g023920)
ZMA: 
542374(mdh6)
SITA: 
ATR: 
s00140p00105610(AMTR_s00140p00105610)
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
Ot08g00890(NADP-MDH)
MIS: 
MICPUN_104869(NADP-MDH)
MPP: 
CSL: 
CVR: 
 » show all
Taxonomy
Reference
1  [PMID:5689906]
  Authors
Connelly JL, Danner DJ, Bowden JA.
  Title
Branched chain alpha-keto acid metabolism. I. Isolation, purification, and partial characterization of bovine liver alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid dehydrogenase.
  Journal
J. Biol. Chem. 243 (1968) 1198-203.
  Organism
Bos taurus
Reference
2  [PMID:4397919]
  Authors
Johnson HS.
  Title
NADP-malate dehydrogenase: photoactivation in leaves of plants with Calvin cycle photosynthesis.
  Journal
Biochem. Biophys. Res. Commun. 43 (1971) 703-9.
  Organism
Zea mays
Reference
3  [PMID:4395182]
  Authors
Johnson HS, Hatch MD.
  Title
Properties and regulation of leaf nicotinamide-adenine dinucleotide phosphate-malate dehydrogenase and 'malic' enzyme in plants with the C4-dicarboxylic acid pathway of photosynthesis.
  Journal
Biochem. J. 119 (1970) 273-80.
  Organism
Zea mays
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-19-4

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