KEGG   ENZYME: 1.1.2.6Help
Entry
EC 1.1.2.6                  Enzyme                                 

Name
polyvinyl alcohol dehydrogenase (cytochrome);
PVA dehydrogenase;
PVADH
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With a cytochrome as acceptor
BRITE hierarchy
Sysname
polyvinyl alcohol:ferricytochrome-c oxidoreductase
Reaction(IUBMB)
polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+ [RN:R03136]
Reaction(KEGG)
Substrate
polyvinyl alcohol [CPD:C00980];
ferricytochrome c [CPD:C00125]
Product
oxidized polyvinyl alcohol [CPD:C01166];
ferrocytochrome c [CPD:C00126];
H+ [CPD:C00080]
Comment
A quinoprotein. The enzyme is involved in bacterial polyvinyl alcohol degradation. Some Gram-negative bacteria degrade polyvinyl alcohol by importing it into the periplasmic space, where it is oxidized by polyvinyl alcohol dehydrogenase, an enzyme that is coupled to the respiratory chain via cytochrome c. The enzyme contains a pyrroloquinoline quinone cofactor.
History
EC 1.1.2.6 created 1989 as EC 1.1.99.23, transferred 2010 to EC 1.1.2.6
Orthology
K05889  
polyvinyl alcohol dehydrogenase (cytochrome)
Genes
XFA: 
XFT: 
XFN: 
XFF: 
XFL: 
XFS: 
XCC: 
XCB: 
XCA: 
XCP: 
XCV: 
XAC: 
XCI: 
XCT: 
XCU: 
XCN: 
XCW: 
XCR: 
XCM: 
XCF: 
XCJ: 
XFU: 
XAX: 
XAO: 
XOO: 
XOM: 
XOO0301(XOO0301)
XOP: 
XOY: 
XOR: 
XOZ: 
XSA: 
XTN: 
ZAL: 
PSPI: 
BCT: 
BCAI: 
EBA: 
p2A321(pvaA)
SUR: 
AGE: 
SCL: 
SCU: 
BJA: 
BJU: 
BJP: 
BRAD: 
PZU: 
NPP: 
SPHP: 
SGI: 
SGRAN_2681(pvadh)
SWI: 
ANH: 
ADO: 
NBR: 
ICA: 
SESP: 
KPHY: 
LED: 
CMP: 
GMA: 
TRS: 
SUS: 
ABAC: 
SLI: 
 » show all
Taxonomy
Reference
1  [PMID:3513704]
  Authors
Shimao M, Ninomiya K, Kuno O, Kato N, Sakazawa C.
  Title
Existence of a novel enzyme, pyrroloquinoline quinone-dependent polyvinyl alcohol dehydrogenase, in a bacterial symbiont, Pseudomonas sp. strain VM15C.
  Journal
Appl. Environ. Microbiol. 51 (1986) 268-75.
Reference
2  [PMID:16347841]
  Authors
Shimao M, Onishi S, Kato N, Sakazawa C.
  Title
Pyrroloquinoline Quinone-Dependent Cytochrome Reduction in Polyvinyl Alcohol-Degrading Pseudomonas sp. Strain VM15C.
  Journal
Appl. Environ. Microbiol. 55 (1989) 275-278.
Reference
3  [PMID:18343342]
  Authors
Mamoto R, Hu X, Chiue H, Fujioka Y, Kawai F
  Title
Cloning and expression of soluble cytochrome c and its role in polyvinyl alcohol  degradation by polyvinyl alcohol-utilizing Sphingopyxis sp. strain 113P3.
  Journal
J. Biosci. Bioeng. 105 (2008) 147-51.
Reference
4  [PMID:16804170]
  Authors
Hirota-Mamoto R, Nagai R, Tachibana S, Yasuda M, Tani A, Kimbara K, Kawai F
  Title
Cloning and expression of the gene for periplasmic poly(vinyl alcohol) dehydrogenase from Sphingomonas sp. strain 113P3, a novel-type quinohaemoprotein  alcohol dehydrogenase.
  Journal
Microbiology. 152 (2006) 1941-9.
  Sequence
Reference
5  [PMID:18214469]
  Authors
Hu X, Mamoto R, Fujioka Y, Tani A, Kimbara K, Kawai F
  Title
The pva operon is located on the megaplasmid of Sphingopyxis sp. strain 113P3 and is constitutively expressed, although expression is enhanced by PVA.
  Journal
Appl. Microbiol. Biotechnol. 78 (2008) 685-93.
Reference
6  [PMID:19590867]
  Authors
Kawai F, Hu X
  Title
Biochemistry of microbial polyvinyl alcohol degradation.
  Journal
Appl. Microbiol. Biotechnol. 84 (2009) 227-37.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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