KEGG   ENZYME: 1.1.3.37Help
Entry
EC 1.1.3.37                 Enzyme                                 
Name
D-arabinono-1,4-lactone oxidase;
D-arabinono-gamma-lactone oxidase;
ALO
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
D-arabinono-1,4-lactone:oxygen oxidoreductase
Reaction(IUBMB)
D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 [RN:R02715]
Reaction(KEGG)
Substrate
D-arabinono-1,4-lactone [CPD:C00652];
O2 [CPD:C00007]
Product
dehydro-D-arabinono-1,4-lactone [CPD:C06316];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD). L-Galactono-1,4-lactone, L-gulono-1,4-lactone and L-xylono-1,4-lactone can also act as substrates but D-glucono-1,5-lactone, L-arabinono-1,4-lactone, D-galactono-1,4-lactone and D-gulono-1,4-lactone cannot [1]. With L-galactono-1,4-lactone as substrate, the product is L-ascorbate [3]. The product dehydro-D-arabinono-1,4-lactone had previously been referred to erroneously as D-erythroascorbate (CAS no.: 5776-48-7; formula: C6H8O6), although it was referred to as a five-carbon compound [1].
Orthology
K00107  
D-arabinono-1,4-lactone oxidase
Genes
SCE: 
YML086C(ALO1)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0C00130(NCAS0C00130)
NDI: 
NDAI_0K00250(NDAI0K00250)
TPF: 
TPHA_0I00160(TPHA0I00160)
TBL: 
TBLA_0B02960(TBLA0B02960)
TDL: 
TDEL_0B00300(TDEL0B00300)
KAF: 
KAFR_0L02030(KAFR0L02030)
DHA: 
DEHA2A02904g
PIC: 
PICST_88335(ALO1)
PGU: 
PGUG_01601
LEL: 
LELG_05374
CAL: 
CaO19.7551(ALO1)
CTP: 
CTRG_05879
CDU: 
CD36_34940
COT: 
CORT_0G01540
YLI: 
YALI0A21263g
CLU: 
CLUG_02182
NCR: 
NCU03188
SMP: 
SMAC_02909
PAN: 
PODANSg4195
TTT: 
THITE_119824
MTM: 
MYCTH_2297573
MGR: 
MGG_02689
FGR: 
FG08694.1
NHE: 
NECHADRAFT_59191
VAL: 
VDBG_01837
SSL: 
SS1G_14188
BFU: 
BC1G_07692
ANI: 
AN0836.2
NFI: 
NFIA_010460
AFM: 
AFUA_1G14950
AOR: 
AOR_1_2134174(AO090005001234)
ANG: 
ANI_1_1278034(An03g03460)
AFV: 
AFLA_084710
ACT: 
ACLA_020400
PCS: 
Pc16g13180
CIM: 
CIMG_03293
CPW: 
CPC735_009020
PBL: 
PAAG_05474
URE: 
UREG_07129
ABE: 
ARB_01878
TVE: 
TRV_07142
AJE: 
HCAG_02422
PNO: 
SNOG_01863
PTE: 
PTT_10151
ZTR: 
MYCGRDRAFT_68116
TML: 
GSTUM_00000898001
 » show all
Taxonomy
Reference
1  [PMID:7957197]
  Authors
Huh WK, Kim ST, Yang KS, Seok YJ, Hah YC, Kang SO.
  Title
Characterisation of D-arabinono-1,4-lactone oxidase from Candida albicans ATCC 10231.
  Journal
Eur. J. Biochem. 225 (1994) 1073-9.
  Organism
Candida albicans [GN:cal]
Reference
2  [PMID:10094636]
  Authors
Huh WK, Lee BH, Kim ST, Kim YR, Rhie GE, Baek YW, Hwang CS, Lee JS, Kang SO.
  Title
D-Erythroascorbic acid is an important antioxidant molecule in Saccharomyces cerevisiae.
  Journal
Mol. Microbiol. 30 (1998) 895-903.
  Organism
Saccharomyces cerevisiae [GN:sce]
Reference
3  [PMID:10508108]
  Authors
Lee BH, Huh WK, Kim ST, Lee JS, Kang SO.
  Title
Bacterial production of D-erythroascorbic acid and L-ascorbic acid through functional expression of Saccharomyces cerevisiae D-arabinono-1,4-lactone oxidase in Escherichia coli.
  Journal
Appl. Environ. Microbiol. 65 (1999) 4685-7.
  Organism
Saccharomyces cerevisiae [GN:sce]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
182372-12-9
DBGET integrated database retrieval system