KEGG   ENZYME: 1.1.3.37Help
Entry
EC 1.1.3.37                 Enzyme                                 

Name
D-arabinono-1,4-lactone oxidase;
D-arabinono-gamma-lactone oxidase;
ALO
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
D-arabinono-1,4-lactone:oxygen oxidoreductase
Reaction(IUBMB)
D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 [RN:R02715]
Reaction(KEGG)
Substrate
D-arabinono-1,4-lactone [CPD:C00652];
O2 [CPD:C00007]
Product
dehydro-D-arabinono-1,4-lactone [CPD:C06316];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD). L-Galactono-1,4-lactone, L-gulono-1,4-lactone and L-xylono-1,4-lactone can also act as substrates but D-glucono-1,5-lactone, L-arabinono-1,4-lactone, D-galactono-1,4-lactone and D-gulono-1,4-lactone cannot [1]. With L-galactono-1,4-lactone as substrate, the product is L-ascorbate [3]. The product dehydro-D-arabinono-1,4-lactone had previously been referred to erroneously as D-erythroascorbate (CAS no.: 5776-48-7; formula: C6H8O6), although it was referred to as a five-carbon compound [1].
History
EC 1.1.3.37 created 1999
Orthology
K00107  
D-arabinono-1,4-lactone oxidase
Genes
SCE: 
YML086C(ALO1)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0C00130(NCAS0C00130)
NDI: 
NDAI_0K00250(NDAI0K00250)
TPF: 
TPHA_0I00160(TPHA0I00160)
TBL: 
TBLA_0B02960(TBLA0B02960)
TDL: 
TDEL_0B00300(TDEL0B00300)
KAF: 
KAFR_0L02030(KAFR0L02030)
DHA: 
PIC: 
PGU: 
LEL: 
SPAA: 
CAL: 
CTP: 
CDU: 
COT: 
CTEN: 
YLI: 
CLU: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_2134174(AO090005001234)
ANG: 
ANI_1_1278034(An03g03460)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
ZTR: 
PFJ: 
BCOM: 
TML: 
LBC: 
GTT: 
 » show all
Taxonomy
Reference
1  [PMID:7957197]
  Authors
Huh WK, Kim ST, Yang KS, Seok YJ, Hah YC, Kang SO.
  Title
Characterisation of D-arabinono-1,4-lactone oxidase from Candida albicans ATCC 10231.
  Journal
Eur. J. Biochem. 225 (1994) 1073-9.
  Organism
Candida albicans
Reference
2  [PMID:10094636]
  Authors
Huh WK, Lee BH, Kim ST, Kim YR, Rhie GE, Baek YW, Hwang CS, Lee JS, Kang SO.
  Title
D-Erythroascorbic acid is an important antioxidant molecule in Saccharomyces cerevisiae.
  Journal
Mol. Microbiol. 30 (1998) 895-903.
  Organism
Saccharomyces cerevisiae
  Sequence
[sce:YML086C]
Reference
3  [PMID:10508108]
  Authors
Lee BH, Huh WK, Kim ST, Lee JS, Kang SO.
  Title
Bacterial production of D-erythroascorbic acid and L-ascorbic acid through functional expression of Saccharomyces cerevisiae D-arabinono-1,4-lactone oxidase in Escherichia coli.
  Journal
Appl. Environ. Microbiol. 65 (1999) 4685-7.
  Organism
Saccharomyces cerevisiae
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
182372-12-9

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