KEGG   ENZYME: 1.1.3.37Help
Entry
EC 1.1.3.37                 Enzyme                                 

Name
D-arabinono-1,4-lactone oxidase;
D-arabinono-gamma-lactone oxidase;
ALO
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
D-arabinono-1,4-lactone:oxygen oxidoreductase
Reaction(IUBMB)
D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2 [RN:R02715]
Reaction(KEGG)
Substrate
D-arabinono-1,4-lactone [CPD:C00652];
O2 [CPD:C00007]
Product
dehydro-D-arabinono-1,4-lactone [CPD:C06316];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD). L-Galactono-1,4-lactone, L-gulono-1,4-lactone and L-xylono-1,4-lactone can also act as substrates but D-glucono-1,5-lactone, L-arabinono-1,4-lactone, D-galactono-1,4-lactone and D-gulono-1,4-lactone cannot [1]. With L-galactono-1,4-lactone as substrate, the product is L-ascorbate [3]. The product dehydro-D-arabinono-1,4-lactone had previously been referred to erroneously as D-erythroascorbate (CAS no.: 5776-48-7; formula: C6H8O6), although it was referred to as a five-carbon compound [1].
History
EC 1.1.3.37 created 1999
Orthology
K00107  D-arabinono-1,4-lactone oxidase
Genes
AQU: 105312928
SCE: YML086C(ALO1)
AGO: AGOS_AFR440C
ERC: Ecym_1386
KLA: KLLA0C16896g
KMX: KLMA_70261(ALO1)
LTH: KLTH0F06820g
VPO: Kpol_309p4
ZRO: ZYRO0A00836g
CGR: CAGL0H04125g
NCS: NCAS_0C00130(NCAS0C00130)
NDI: NDAI_0K00250(NDAI0K00250)
TPF: TPHA_0I00160(TPHA0I00160)
TBL: TBLA_0B02960(TBLA0B02960)
TDL: TDEL_0B00300(TDEL0B00300)
KAF: KAFR_0L02030(KAFR0L02030)
PIC: PICST_88335(ALO1)
CAL: CAALFM_CR09790WA(ALO1)
CAUR: QG37_03859
SLB: AWJ20_4935(ALO1)
NCR: NCU03188
NTE: NEUTE1DRAFT150135(NEUTE1DRAFT_150135)
MGR: MGG_02689
MAW: MAC_04878
MAJ: MAA_09098
CMT: CCM_03419
BFU: BCIN_09g06500(Bcalo1)
MBE: MBM_09631
ANI: AN0836.2
ANG: ANI_1_1278034(An03g03460)
ABE: ARB_01878
TVE: TRV_07142
PTE: PTT_10151
SPO: SPAPB1A10.12c(alo1)
 » show all
Taxonomy
Reference
1  [PMID:7957197]
  Authors
Huh WK, Kim ST, Yang KS, Seok YJ, Hah YC, Kang SO.
  Title
Characterisation of D-arabinono-1,4-lactone oxidase from Candida albicans ATCC 10231.
  Journal
Eur. J. Biochem. 225 (1994) 1073-9.
Reference
2  [PMID:10094636]
  Authors
Huh WK, Lee BH, Kim ST, Kim YR, Rhie GE, Baek YW, Hwang CS, Lee JS, Kang SO.
  Title
D-Erythroascorbic acid is an important antioxidant molecule in Saccharomyces cerevisiae.
  Journal
Mol. Microbiol. 30 (1998) 895-903.
  Sequence
[sce:YML086C]
Reference
3  [PMID:10508108]
  Authors
Lee BH, Huh WK, Kim ST, Lee JS, Kang SO.
  Title
Bacterial production of D-erythroascorbic acid and L-ascorbic acid through functional expression of Saccharomyces cerevisiae D-arabinono-1,4-lactone oxidase in Escherichia coli.
  Journal
Appl. Environ. Microbiol. 65 (1999) 4685-7.
Other DBs
ExplorEnz - The Enzyme Database: 1.1.3.37
IUBMB Enzyme Nomenclature: 1.1.3.37
ExPASy - ENZYME nomenclature database: 1.1.3.37
BRENDA, the Enzyme Database: 1.1.3.37
CAS: 182372-12-9

DBGET integrated database retrieval system