KEGG   ENZYME: 1.1.98.2Help
Entry
EC 1.1.98.2                 Enzyme                                 

Name
glucose-6-phosphate dehydrogenase (coenzyme-F420);
coenzyme F420-dependent glucose-6-phosphate dehydrogenase;
F420-dependent glucose-6-phosphate dehydrogenase;
FGD1;
Rv0407;
F420-dependent glucose-6-phosphate dehydrogenase 1
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With other, known, physiological acceptors
BRITE hierarchy
Sysname
D-glucose-6-phosphate:F420 1-oxidoreductase
Reaction(IUBMB)
D-glucose 6-phosphate + oxidized coenzyme F420 = 6-phospho-D-glucono-1,5-lactone + reduced coenzyme F420 [RN:R09550]
Reaction(KEGG)
Substrate
D-glucose 6-phosphate [CPD:C00092];
oxidized coenzyme F420 [CPD:C00876]
Product
6-phospho-D-glucono-1,5-lactone [CPD:C01236];
reduced coenzyme F420 [CPD:C01080]
Comment
The enzyme is very specific for D-glucose 6-phosphate. No activity with NAD+, NADP+, FAD and FMN [1].
History
EC 1.1.98.2 created 2010 as EC 1.1.99.34, transferred 2011 to EC 1.1.98.2
Orthology
K15510  
coenzyme F420-dependent glucose-6-phosphate dehydrogenase
Genes
MTU: 
Rv0407(fgd1)
MTV: 
MTC: 
MT0420(fgd)
MRA: 
MRA_0413(fgd1)
MTF: 
MTB: 
MTK: 
MTZ: 
MTI: 
MTE: 
MTUR: 
CFBS_0423(fgd1)
MTL: 
MTO: 
MTD: 
UDA_0407(fgd1)
MTN: 
MTJ: 
MTUB: 
MTUE: 
MTX: 
MTUL: 
MTUT: 
MTUU: 
MTQ: 
MBO: 
Mb0415(fgd1)
MBB: 
BCG_0446(fgd1)
MBT: 
JTY_0416(fgd1)
MBM: 
MBK: 
MBX: 
MBZ: 
MAF: 
MAF_04090(fgd1)
MCE: 
MCQ: 
MCV: 
MCX: 
MCZ: 
MMIC: 
MLE: 
MLB: 
MPA: 
MAO: 
MAVI: 
MAVU: 
MAV: 
MAVD: 
MAVR: 
MAVA: 
MIT: 
MIR: 
MIA: 
MIE: 
MID: 
MYO: 
MSM: 
MSG: 
MSB: 
MSN: 
MSH: 
MSA: 
MUL: 
MUL_2814(fgd1)
MVA: 
MGI: 
MSP: 
MAB: 
MABB: 
MMV: 
MAY: 
MABO: 
MABL: 
MAZ: 
MAK: 
MYS: 
MYC: 
MMC: 
MKM: 
MJL: 
MJD: 
MMI: 
MMAR_0709(fgd1)
MRH: 
MMM: 
MCB: 
MLI: 
MKN: 
MKS: 
MKI: 
MNE: 
MYV: 
MYE: 
MGO: 
MFT: 
MHAD: 
MPHL: 
MVQ: 
ASD: 
NFA: 
NFR: 
NCY: 
NBR: 
NNO: 
RHA: 
RER: 
REY: 
REB: 
ROP: 
ROA: 
REQ: 
RPY: 
RHB: 
RAV: 
RFA: 
GBR: 
GPO: 
GOR: 
GOQ: 
GTA: 
TPR: 
SRT: 
MTS: 
MIO: 
MCW: 
RTX: 
RTC: 
RTN: 
MVD: 
AGY: 
BCV: 
LMOI: 
ICA: 
ARS: 
KFL: 
NML: 
KRA: 
AMD: 
AMN: 
AMM: 
AMZ: 
AOI: 
AJA: 
AMQ: 
ALU: 
PDX: 
PSEE: 
PSEH: 
PSEQ: 
PECQ: 
PHH: 
SESP: 
BN6_24600(fgd1)
AHM: 
AMS: 
ASE: 
ACTN: 
AFS: 
CWO: 
MBA: 
MBAK: 
MMA: 
MMAZ: 
MMJ: 
MTHE: 
MTHR: 
MHOR: 
MBG: 
MEMA: 
MPD: 
MEZ: 
Mtc_2316(fgd-2)
RCI: 
RRC242(fgd-2)
HXA: 
SALI: 
NGA: 
NVN: 
NEV: 
TAA: 
NMY3_01705(fgd1_3) NMY3_01719(fgd1_4)
CSU: 
 » show all
Taxonomy
Reference
1  [PMID:8631674]
  Authors
Purwantini E, Daniels L
  Title
Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis.
  Journal
J. Bacteriol. 178 (1996) 2861-6.
  Sequence
Reference
2  [PMID:17376702]
  Authors
Bashiri G, Squire CJ, Baker EN, Moreland NJ
  Title
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis  expression system.
  Journal
Protein. Expr. Purif. 54 (2007) 38-44.
  Sequence
[mtu:Rv0407]
Reference
3  [PMID:8997717]
  Authors
Purwantini E, Gillis TP, Daniels L
  Title
Presence of F420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea.
  Journal
FEMS. Microbiol. Lett. 146 (1997) 129-34.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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