| Entry |
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| Name |
glucose-6-phosphate dehydrogenase (coenzyme-F420);
coenzyme F420-dependent glucose-6-phosphate dehydrogenase;
F420-dependent glucose-6-phosphate dehydrogenase;
FGD1;
Rv0407;
F420-dependent glucose-6-phosphate dehydrogenase 1
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With other, known, physiological acceptors
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| Sysname |
D-glucose-6-phosphate:F420 1-oxidoreductase
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| Reaction(IUBMB) |
D-glucose 6-phosphate + oxidized coenzyme F420 = 6-phospho-D-glucono-1,5-lactone + reduced coenzyme F420 [RN: R09550]
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| Reaction(KEGG) |
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| Substrate |
D-glucose 6-phosphate [CPD: C00092];
oxidized coenzyme F420 [CPD: C00876]
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| Product |
6-phospho-D-glucono-1,5-lactone [CPD: C01236];
reduced coenzyme F420 [CPD: C01080]
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| Comment |
The enzyme is very specific for D-glucose 6-phosphate. No activity with NAD+, NADP+, FAD and FMN [1].
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| History |
EC 1.1.98.2 created 2010 as EC 1.1.99.34, transferred 2011 to EC 1.1.98.2
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| Orthology |
| coenzyme F420-dependent glucose-6-phosphate dehydrogenase |
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| Genes |
MTU: | | MTV: | | MTC: | | MRA: | | MTF: | | MTB: | | MTK: | | MTZ: | | MTG: | | MTI: | | MTE: | | MTUR: | | MTL: | | MTO: | | MTD: | | MTN: | | MTJ: | | MTUB: | | MTUE: | | MTX: | | MTUL: | | MTUT: | | MTUU: | | MTQ: | | MBO: | | MBB: | | MBT: | | MBM: | | MBK: | | MBX: | | MBZ: | | MAF: | | MCE: | | MCQ: | | MCV: | | MCX: | | MCZ: | | MMIC: | | MLE: | | MLB: | | MPA: | | MAO: | | MAVI: | | MAVU: | | MAV: | | MAVD: | | MAVR: | | MAVA: | | MIT: | | MIA: | | MIE: | | MIR: | | MID: | | MYO: | | MCHI: | | MMAL: | | MSM: | | MSG: | | MSB: | | MSN: | | MSH: | | MVA: | | MGI: | | MSP: | | MCB: | | MNE: | | MGO: | | MFT: | | MPHL: | | MVQ: | | MLL: | | MSA: | | MUL: | | MAB: | | MABB: | | MMV: | | MAY: | | MABO: | | MABL: | | MAZ: | | MAK: | | MYS: | | MYC: | | MCHE: | | MIZ: | | MSTE: | | MMC: | | MKM: | | MJL: | | MJD: | | MMI: | | MMAE: | | MRH: | | MMM: | | MLI: | | MKN: | | MKS: | | MKI: | | MYV: | | MYE: | | MHAD: | | MYN: | | MDX: | | ASD: | | NFA: | | NFR: | | NCY: | | NBR: | | NNO: | | NSL: | | NSR: | | NTP: | | RHA: | | RER: | | REY: | | REB: | | ROP: | | ROA: | | REQ: | | RPY: | | RHB: | | RAV: | | RFA: | | RHW: | | RHS: | | RRZ: | | RHU: | | RQI: | | GBR: | | GPO: | | GOR: | | GOQ: | | GTA: | | GOC: | | TPR: | | TSM: | | SRT: | | DTM: | | MTS: | | MIO: | | MCW: | | MIH: | | RTX: | | RTC: | | RTN: | | MVD: | | AGY: | | CPHY: | | BCV: | | LMOI: | | ICA: | | ARS: | | KFL: | | NML: | | KRA: | | AMD: | | AMN: | | AMM: | | AMZ: | | AOI: | | AJA: | | AMQ: | | AMYC: | | AMYB: | | PDX: | | PSEE: | | PSEH: | | PSEQ: | | PECQ: | | PHH: | | SESP: | | AHM: | | ACTI: | | ACAD: | | AHG: | | ACTA: | | PMAD: | | AMS: | | ASE: | | ACTN: | | AFS: | | CWO: | | MBA: | | MBW: | | MBAK: | | MMA: | | MMAZ: | | MMJ: | | MMAC: | | MTHE: | | MTHR: | | MHOR: | | MPD: | | RCI: | | HXA: | | SALI: | | NGA: | | NVN: | | NEV: | | TAA: | | CSU: | |
» show all
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| Reference |
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| Authors |
Purwantini E, Daniels L |
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| Title |
Purification of a novel coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis. |
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| Journal |
J. Bacteriol. 178 (1996) 2861-6. |
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| Sequence |
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| Reference |
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| Authors |
Bashiri G, Squire CJ, Baker EN, Moreland NJ |
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| Title |
Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system. |
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| Journal |
Protein. Expr. Purif. 54 (2007) 38-44. |
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| Sequence |
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| Reference |
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| Authors |
Purwantini E, Gillis TP, Daniels L |
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| Title |
Presence of F420-dependent glucose-6-phosphate dehydrogenase in Mycobacterium and Nocardia species, but absence from Streptomyces and Corynebacterium species and methanogenic Archaea. |
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| Journal |
FEMS. Microbiol. Lett. 146 (1997) 129-34. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |
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