KEGG   ENZYME: 1.1.99.32Help
Entry
EC 1.1.99.32                Enzyme                                 

Name
L-sorbose 1-dehydrogenase;
SDH
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With other acceptors
BRITE hierarchy
Sysname
L-sorbose:acceptor 1-oxidoreductase
Reaction(IUBMB)
L-sorbose + acceptor = 1-dehydro-L-sorbose + reduced acceptor [RN:R09551]
Reaction(KEGG)
Substrate
L-sorbose [CPD:C00247];
acceptor [CPD:C00028]
Product
1-dehydro-L-sorbose [CPD:C19679];
reduced acceptor [CPD:C00030]
Comment
The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. The activity of this membrane-bound enzyme is stimulated by Fe(III) or Co2+ but is inhibited by Cu2+. The enzyme is highly specific for L-sorbose as other sugars, such as glucose, mannitol and sorbitol, are not substrates. Phenazine methosulfate and DCIP can act as artificial acceptors.
History
EC 1.1.99.32 created 2008
Reference
1
  Authors
Sugisawa, T., Hoshino, T., Nomura, S. and Fujiwara, A.
  Title
Isolation and characterization of membrane-bound L-sorbose dehydrogenase from Gluconobacter melanogenus UV10.
  Journal
Agric. Biol. Chem. 55 (1991) 363-370.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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