KEGG   ENZYME: 1.1.99.35Help
Entry
EC 1.1.99.35                Enzyme                                 

Name
soluble quinoprotein glucose dehydrogenase;
soluble glucose dehydrogenase;
sGDH;
glucose dehydrogenase (PQQ-dependent)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With other acceptors
BRITE hierarchy
Sysname
D-glucose:acceptor oxidoreductase
Reaction(IUBMB)
D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor [RN:R10411]
Reaction(KEGG)
Substrate
D-glucose [CPD:C00031];
acceptor [CPD:C00028]
Product
D-glucono-1,5-lactone [CPD:C00198];
reduced acceptor [CPD:C00030]
Comment
Soluble periplasmic enzyme containing PQQ as prosthetic group, bound to a calcium ion. Electron acceptor is not known. It is assayed with Wurster's Blue or phenazine methosulphate. It has negligible sequence or structure similarity to other quinoproteins. It catalyses an exceptionally high rate of oxidation of a wide range of aldose sugars, including D-glucose, galactose, arabinose and xylose, and also the disaccharides lactose, cellobiose and maltose. It has been described only in Acinetobacter calcoaceticus.
History
EC 1.1.99.35 created 2010
Reference
1
  Authors
Geiger, O. and Gorisch, H.
  Title
Crystalline quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus.
  Journal
Biochemistry 25 (1986) 6043-6048.
Reference
2  [PMID:3800975]
  Authors
Dokter P, Frank J, Duine JA
  Title
Purification and characterization of quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus L.M.D. 79.41.
  Journal
Biochem. J. 239 (1986) 163-7.
  Organism
Acinetobacter calcoaceticus
Reference
3  [PMID:2834325]
  Authors
Cleton-Jansen AM, Goosen N, Wenzel TJ, van de Putte P
  Title
Cloning of the gene encoding quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus: evidence for the presence of a second enzyme.
  Journal
J. Bacteriol. 170 (1988) 2121-5.
  Organism
Acinetobacter calcoaceticus
Reference
4  [PMID:2551369]
  Authors
Matsushita K, Shinagawa E, Adachi O, Ameyama M
  Title
Quinoprotein D-glucose dehydrogenase of the Acinetobacter calcoaceticus respiratory chain: membrane-bound and soluble forms are different molecular species.
  Journal
Biochemistry. 28 (1989) 6276-80.
  Organism
Acinetobacter calcoaceticus
Reference
5  [PMID:10933491]
  Authors
Oubrie A, Dijkstra BW
  Title
Structural requirements of pyrroloquinoline quinone dependent enzymatic reactions.
  Journal
Protein. Sci. 9 (2000) 1265-73.
  Organism
Acinetobacter calcoaceticus
Reference
6
  Authors
Matsushita, K., Toyama, H., Ameyama, M., Adachi, O., Dewanti, A. and Duine, J.A.
  Title
Soluble and membrane-bound quinoprotein D-glucose dehydrogenases of the Acinetobacter calcoaceticus : the binding process of PQQ to the apoenzymes.
  Journal
Biosci. Biotechnol. Biochem. 59 (1995) 1548-1555.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system