KEGG   ENZYME: 1.10.3.13Help
Entry
EC 1.10.3.13                Enzyme                                 

Name
caldariellaquinol oxidase (H+-transporting);
SoxABCD quinol oxidase;
SoxABCD complex;
quinol oxidase SoxABCD;
SoxM supercomplex;
aa3-type quinol oxidase;
aa3 quinol oxidase;
cytochrome aa3;
terminal quinol oxidase;
terminal quinol:oxygen oxidoreductase;
caldariella quinol:dioxygen oxidoreductase;
cytochrome aa3-type oxidase ;
caldariellaquinol:O2 oxidoreductase (H+-transporting)
Class
Oxidoreductases;
Acting on diphenols and related substances as donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
caldariellaquinol:oxygen oxidoreductase (H+-transporting)
Reaction(IUBMB)
2 caldariellaquinol + O2 + n H+[side 1] = 2 caldariellaquinone + 2 H2O + n H+[side 2] [RN:R10444]
Reaction(KEGG)
Substrate
caldariellaquinol [CPD:C20623];
O2 [CPD:C00007];
H+[side 1]
Product
caldariellaquinone [CPD:C20624];
H2O [CPD:C00001];
H+[side 2]
Comment
A copper-containing cytochrome. The enzyme from thermophilic archaea is part of the terminal oxidase and catalyses the reduction of O2 to water, accompanied by the extrusion of protons across the cytoplasmic membrane.
History
EC 1.10.3.13 created 2013
Reference
1  [PMID:9079667]
  Authors
Gleissner M, Kaiser U, Antonopoulos E, Schafer G
  Title
The archaeal SoxABCD complex is a proton pump in Sulfolobus acidocaldarius.
  Journal
J. Biol. Chem. 272 (1997) 8417-26.
Reference
2  [PMID:9023221]
  Authors
Purschke WG, Schmidt CL, Petersen A, Schafer G
  Title
The terminal quinol oxidase of the hyperthermophilic archaeon Acidianus ambivalens exhibits a novel subunit structure and gene organization.
  Journal
J. Bacteriol. 179 (1997) 1344-53.
Reference
3  [PMID:11115638]
  Authors
Gilderson G, Aagaard A, Gomes CM, Adelroth P, Teixeira M, Brzezinski P
  Title
Kinetics of electron and proton transfer during O(2) reduction in cytochrome aa(3) from A. ambivalens: an enzyme lacking Glu(I-286).
  Journal
Biochim. Biophys. Acta. 1503 (2001) 261-70.
Reference
4  [PMID:12530544]
  Authors
Komorowski L, Verheyen W, Schafer G
  Title
The archaeal respiratory supercomplex SoxM from S. acidocaldarius combines features of quinole and cytochrome c oxidases.
  Journal
Biol. Chem. 383 (2002) 1791-9.
Reference
5  [PMID:15306018]
  Authors
Muller FH, Bandeiras TM, Urich T, Teixeira M, Gomes CM, Kletzin A.
  Title
Coupling of the pathway of sulphur oxidation to dioxygen reduction: characterization of a novel membrane-bound thiosulphate:quinone oxidoreductase.
  Journal
Mol. Microbiol. 53 (2004) 1147-60.
Reference
6  [PMID:16163550]
  Authors
Bandeiras TM, Pereira MM, Teixeira M, Moenne-Loccoz P, Blackburn NJ
  Title
Structure and coordination of CuB in the Acidianus ambivalens aa3 quinol oxidase  heme-copper center.
  Journal
J. Biol. Inorg. Chem. 10 (2005) 625-35.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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