| Entry |
|
|---|
| Name |
catechol 1,2-dioxygenase;
catechol-oxygen 1,2-oxidoreductase;
1,2-pyrocatechase;
catechase;
catechol 1,2-oxygenase;
catechol dioxygenase;
pyrocatechase;
pyrocatechol 1,2-dioxygenase;
CD I;
CD II |
|---|
| Class |
Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of
oxygen into the substrate (oxygenases). The oxygen incorporated need
not be derived from O2;
With incorporation of two atoms of oxygen
 |
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| Sysname |
catechol:oxygen 1,2-oxidoreductase |
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| Reaction(IUBMB) |
catechol + O2 = cis,cis-muconate [RN:R00817] |
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| Reaction(KEGG) |
R00817;
(other) R04258 R05299 R06833 R06839 R08114 R08115
 |
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| Substrate |
catechol [CPD:C00090];
O2 [CPD:C00007] |
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| Product |
cis,cis-muconate [CPD:C02480] |
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| Cofactor |
Iron [CPD:C00023] |
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| Comment |
Requires Fe3+. Involved in the metabolism of nitro-aromatic
compounds by a strain of Pseudomonas putida. |
|---|
| Pathway |
PATH: ec00361 gamma-Hexachlorocyclohexane degradation
PATH: ec00362 Benzoate degradation via hydroxylation
PATH: ec00364 Fluorobenzoate degradation
PATH: ec00622 Toluene and xylene degradation
PATH: ec00627 1,4-Dichlorobenzene degradation
PATH: ec00629 Carbazole degradation
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K03381 catechol 1,2-dioxygenase |
|---|
| Genes |
EFE: EFER_1481(catA)
KPN: KPN_01873
KPE: KPK_2483(catA)
KPU: KP1_2939
PAE: PA2507(catA)
PAU: PA14_32240(catA)
PAP: PSPA7_2732(catA) PSPA7_3907
PAG: PLES_27881(catA)
PPU: PP_3166 PP_3713(catA)
PPF: Pput_2055 Pput_2549
PPG: PputGB1_2206 PputGB1_2683
PPW: PputW619_2703
PFL: PFL_3860(catA)
PFO: Pfl01_2327 Pfl01_2961
PFS: PFLU5190
PEN: PSEEN3136(catA)
PSA: PST_1674(catA)
PCR: Pcryo_1268
ACI: ACIAD1442(catA)
ACB: A1S_1845
ABM: ABSDF1996(catA)
ABY: ABAYE1718(catA)
ABC: ACICU_01958
ABN: AB57_2181(catA)
ABB: ABBFA_001608(catA)
NOC: Noc_1128 Noc_2416
MMW: Mmwyl1_3040
RPI: Rpic_1363
RPF: Rpic12D_1427
REU: Reut_A1587 Reut_A1705 Reut_B4137 Reut_B4402 Reut_D6466
Reut_D6473
REH: H16_A1964(catA) H16_B0968(pcpA)
RME: Rmet_1781 Rmet_4881 Rmet_5062
CTI: RALTA_B1412
BMA: BMAA0199(catA)
BMV: BMASAVP1_1374(catA)
BML: BMA10229_1571(catA)
BMN: BMA10247_A0230(catA)
BPS: BPSS1892(catA)
BPM: BURPS1710b_A0987(catA)
BPL: BURPS1106A_A2567(catA)
BPD: BURPS668_A2711(catA)
BPR: GBP346_A0963
BTE: BTH_II0484
BVI: Bcep1808_4158 Bcep1808_5824
BUR: Bcep18194_A4486 Bcep18194_B2329 Bcep18194_C7045
BCN: Bcen_1307 Bcen_4594
BCH: Bcen2424_3769 Bcen2424_6523
BCM: Bcenmc03_1327 Bcenmc03_3754 Bcenmc03_6130
BCJ: BCAL1342 BCAM0804(catA1) BCAS0497(catA2)
BAM: Bamb_3333 Bamb_6585
BAC: BamMC406_3378 BamMC406_3661 BamMC406_6300
BMU: Bmul_3237 Bmul_4961 Bmul_6070
BMJ: BMULJ_03553(catA) BMULJ_05288(catA) BMULJ_05458
BXE: Bxe_A1130(clcA) Bxe_A2109(catA)
BPH: Bphy_4028 Bphy_5624
BPY: Bphyt_1590 Bphyt_2152 Bphyt_4110
BGL: bglu_2g07160
BPT: Bpet1400(catA2) Bpet1534(clcA) Bpet3748(catA1)
POL: Bpro_2064
PNA: Pnap_2116
AJS: Ajs_0142
VEI: Veis_4613
DAC: Daci_1867 Daci_3128
DIA: Dtpsy_0160
VAP: Vapar_0130 Vapar_5310 Vapar_6138
LCH: Lcho_0834
ARA: Arad_12211(catA) Arad_7159
AVI: Avi_7443
RET: RHE_CH02298(ypch00749)
RLE: pRL120093 pRL120101 pRL120214
RLT: Rleg2_3458 Rleg2_5728
RLG: Rleg_5533 Rleg_5541
RHI: NGR_b05930
BRA: BRADO0539 BRADO2264 BRADO2272 BRADO2470
BBT: BBta_2816 BBta_7639
RPC: RPC_3196
RPD: RPD_2210
RPT: Rpal_2441
XAU: Xaut_4357 Xaut_4739
AZC: AZC_1414
MET: M446_1328
MNO: Mnod_0748 Mnod_2372 Mnod_8639
PDE: Pden_1176
DSH: Dshi_0961
NAR: Saro_3830
SWI: Swit_0977 Swit_4890 Swit_5041 Swit_5063
MSM: MSMEG_1911(catA)
MGI: Mflv_1358
MMC: Mmcs_1376
MKM: Mkms_1394
MJL: Mjls_1410
CGL: NCgl1113(cgl1160) NCgl2319(cgl2402)
CGB: cg1311(catA2) cg2636(catA1) cg3385(catA3)
CGT: cgR_1242 cgR_2284 cgR_2941
RHA: RHA1_ro02373(catA1) RHA1_ro02515(catA2) RHA1_ro02997
RHA1_ro08069 RHA1_ro08511
RER: RER_54230(catA)
ROP: ROP_20870(catA) ROP_22420(catA) ROP_42970
GBR: Gbro_4154
ART: Arth_1933
ACH: Achl_4566 Achl_4569
NCA: Noca_0836
SEN: SACE_4382(catA1)
SVI: Svir_19220
CAI: Caci_4340
 |
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| Structures |
PDB: 1DLM 1DLQ 1DLT 1DMH 1S9A 2AZQ 2BOY 3HGI 3HHX 3HHY
3HJ8 3HJQ 3HJS 3HKP 3I4V 3I4Y 3I51 |
|---|
Reference
Authors
Title
Journal
|
1
Hayaishi, O.
Direct oxygenation by O2, oxygenases.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 8, Academic Press, New York, 1963, p. 353-371. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13502352]
HAYAISHI O, KATAGIRI M, ROTHBERG S.
Studies on oxygenases; pyrocatechase.
J. Biol. Chem. 229 (1957) 905-20.
Pseudomonas fluorescens |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:13211620]
SISTROM WR, STANIER RY.
The mechanism of formation of beta-ketoadipic acid by bacteria.
J. Biol. Chem. 210 (1954) 821-36.
Pseudomonas fluorescens |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:3752997]
Zeyer J, Kocher HP, Timmis KN.
Influence of para-substituents on the oxidative metabolism of
o-nitrophenols by Pseudomonas putida B2.
Appl. Environ. Microbiol. 52 (1986) 334-9.
Pseudomonas putida |
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| Other DBs |
ExplorEnz - The Enzyme Database: 1.13.11.1
IUBMB Enzyme Nomenclature: 1.13.11.1
ExPASy - ENZYME nomenclature database: 1.13.11.1
UM-BBD (Biocatalysis/Biodegradation Database): 1.13.11.1
BRENDA, the Enzyme Database: 1.13.11.1
CAS: 9027-16-1 |
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