KEGG   ENZYME: 1.13.11.56Help
Entry
EC 1.13.11.56               Enzyme                                 

Name
1,2-dihydroxynaphthalene dioxygenase;
1,2-DHN dioxygenase;
DHNDO;
1,2-dihydroxynaphthalene oxygenase;
1,2-dihydroxynaphthalene:oxygen oxidoreductase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
naphthalene-1,2-diol:oxygen oxidoreductase
Reaction(IUBMB)
naphthalene-1,2-diol + O2 = 2-hydroxy-2H-chromene-2-carboxylate [RN:R04117]
Reaction(KEGG)
Substrate
naphthalene-1,2-diol [CPD:C03012];
O2 [CPD:C00007]
Product
2-hydroxy-2H-chromene-2-carboxylate [CPD:C06204]
Comment
This enzyme is involved in naphthalene degradation. Requires Fe2+.
History
EC 1.13.11.56 created 2010, modified 2010
Pathway
Naphthalene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K14583  
1,2-dihydroxynaphthalene dioxygenase
Genes
PSC: 
PSTU: 
PBM: 
RMN: 
BMK: 
DM80_1447(doxG)
PNA: 
Taxonomy
Reference
1  [PMID:2050635]
  Authors
Kuhm AE, Stolz A, Ngai KL, Knackmuss HJ
  Title
Purification and characterization of a 1,2-dihydroxynaphthalene dioxygenase from  a bacterium that degrades naphthalenesulfonic acids.
  Journal
J. Bacteriol. 173 (1991) 3795-802.
  Sequence
Reference
2  [PMID:16804169]
  Authors
Keck A, Conradt D, Mahler A, Stolz A, Mattes R, Klein J
  Title
Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6.
  Journal
Microbiology. 152 (2006) 1929-40.
  Sequence
Reference
3  [PMID:7204331]
  Authors
Patel TR, Barnsley EA
  Title
Naphthalene metabolism by pseudomonads: purification and properties of 1,2-dihydroxynaphthalene oxygenase.
  Journal
J. Bacteriol. 143 (1980) 668-73.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 

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