KEGG   ENZYME: 1.13.12.1Help
Entry
EC 1.13.12.1                Enzyme                                 

Name
arginine 2-monooxygenase;
arginine monooxygenase;
arginine decarboxylase;
arginine oxygenase (decarboxylating);
arginine decarboxy-oxidase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
BRITE hierarchy
Sysname
L-arginine:oxygen 2-oxidoreductase (decarboxylating)
Reaction(IUBMB)
L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O [RN:R00559]
Reaction(KEGG)
Substrate
L-arginine [CPD:C00062];
O2 [CPD:C00007]
Product
4-guanidinobutanamide [CPD:C03078];
CO2 [CPD:C00011];
H2O [CPD:C00001]
Comment
A flavoprotein. Also acts on canavanine and homoarginine.
History
EC 1.13.12.1 created 1972
Pathway
Arginine and proline metabolism
Reference
1  [PMID:4295160]
  Authors
Olomucki A, Pho DB, Lebar R, Delcambe L, Thoai NV.
  Title
[Arginine oxygenase (decarboxylating). V. Purification and flavin nature]
  Journal
Biochim. Biophys. Acta. 151 (1968) 353-66.
Reference
2
  Authors
Thoai, N.V. and Olomucki, A.
  Title
Arginine decarboxy-oxydase. I. Caracteres et nature de l'enzyme.
  Journal
Biochim. Biophys. Acta 59 (1962) 533-544.
Reference
3
  Authors
Thoai, N.V. and Olomucki, A.
  Title
Arginine decarboxy-oxydase. II. Oxydation de la canavanine et de l'homoarginine en beta-guanidopropionamide et en delta-guanidovaleramide.
  Journal
Biochim. Biophys. Acta 59 (1962) 545-552.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9027-36-5

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