KEGG   ENZYME: 1.13.12.3Help
Entry
EC 1.13.12.3                Enzyme                                 
Name
tryptophan 2-monooxygenase
Class
Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2;
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
BRITE hierarchy
Sysname
L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)
Reaction(IUBMB)
L-tryptophan + O2 = (indol-3-yl)acetamide + CO2 + H2O [RN:R00679]
Reaction(KEGG)
Substrate
L-tryptophan [CPD:C00078];
O2 [CPD:C00007]
Product
(indol-3-yl)acetamide [CPD:C02693];
CO2 [CPD:C00011];
H2O [CPD:C00001]
Pathway
Tryptophan metabolism
Orthology
K00466  
tryptophan 2-monooxygenase
Genes
DDD: 
DZE: 
PAP: 
PPU: 
PPF: 
PPG: 
PPW: 
PPT: 
PPB: 
PPI: 
PPX: 
T1E_2171
PPUH: 
B479_02390
PPUU: 
PputUW4_04962(iaaM)
PST: 
PSPTO_0518
PSB: 
Psyr_1536 Psyr_4667
PSP: 
PSPPH_4701
PFL: 
PFL_5670
PFO: 
Pfl01_5154
PFS: 
PFLU5595 PFLU5656
PFE: 
PSF113_5381
PFC: 
PflA506_4896
PPZ: 
H045_18360
PEN: 
PSEEN0401
PBA: 
PSEBR_a5163
PDR: 
H681_11755
RSO: 
RSc3151
RSC: 
RCFBP_10283
RSL: 
RPSI07_0329
RSN: 
RSPO_c00326
BVI: 
Bcep1808_4425
BCM: 
Bcenmc03_4304
BXE: 
Bxe_C1245
BPH: 
Bphy_7769
BGE: 
BC1002_6868
BUK: 
MYA_4068
BPX: 
BUPH_04753
ATU: 
Atu6011(tms1)
AVI: 
Avi_8288(tms1)
LCC: 
B488_04010
RDE: 
RD1_1495
RLI: 
RLO149_c032070
ACR: 
Acry_2670
AMV: 
ACMV_29960
APB: 
SAR116_1765
MAB: 
MAB_0818
MMV: 
MYCMA_0419(iaaM)
ASD: 
AS9A_4558
RHA: 
RHA1_ro03531
RER: 
RER_05790
ROP: 
ROP_33250
GPO: 
GPOL_c37600
TPR: 
Tpau_1414
SCO: 
SCO1454(SCL6.11c)
SMA: 
SAV_6893
SGR: 
SGR_6070
SCB: 
SCAB_75511
SSX: 
SACTE_0868
SVL: 
Strvi_3092
SCT: 
SCAT_5364
SCY: 
SCATT_53630
SFA: 
Sfla_5404
SBH: 
SBI_00391 SBI_02339
SHY: 
SHJG_2887
SHO: 
SHJGH_2651
SVE: 
SVEN_1051
SDV: 
BN159_7134
SALB: 
XNR_5396
STRP: 
F750_1215
ART: 
Arth_1110
AAU: 
AAur_1221
ACH: 
Achl_1186
APN: 
Asphe3_11460
ARR: 
ARUE_c11570(iaaM)
NDA: 
Ndas_3618
NAL: 
B005_0760
GOB: 
Gobs_1732
BSD: 
BLASA_1708
KRA: 
Krad_1432
AMD: 
AMED_6946
AMN: 
RAM_35635
AMM: 
AMES_6839
CAI: 
Caci_8157
 » show all
Taxonomy
Reference
1  [PMID:5916389]
  Authors
Kosuge T, Heskett MG, Wilson EE.
  Title
Microbial synthesis and degradation of indole-3-acetic acid. I. The conversion of L-tryptophan to indole-3-acetamide by an enzyme system from Pseudomonas savastanoi.
  Journal
J. Biol. Chem. 241 (1966) 3738-44.
  Organism
Pseudomonas savastanoi
Reference
2
  Authors
Kuo, T.T. and Kosuge, T.
  Title
Factors influencing the production and further metabolism of indole-3-acetic acid by Pseudomonas savastanoi.
  Journal
J. Gen. Appl. Microbiol. 15 (1969) 51-63.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37256-65-8
DBGET integrated database retrieval system