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Entry
EC 1.14.11.15               Enzyme                                 

Name
gibberellin 3beta-dioxygenase;
gibberellin 3beta-hydroxylase;
(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
BRITE hierarchy
Sysname
(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)
Reaction(IUBMB)
gibberellin 20 + 2-oxoglutarate + O2 = gibberellin 1 + succinate + CO2 [RN:R03009]
Reaction(KEGG)
R03009;
(other) R06336
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Substrate
gibberellin 20 [CPD:C02035];
2-oxoglutarate [CPD:C00026];
O2 [CPD:C00007]
Product
gibberellin 1 [CPD:C00859];
succinate [CPD:C00042];
CO2 [CPD:C00011]
Comment
Requires Fe2+ and ascorbate.
History
EC 1.14.11.15 created 1992
Pathway
Diterpenoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K04124  
gibberellin 3-beta-dioxygenase
Genes
ATH: 
AT1G15550(GA3OX1) AT1G80330(GA3OX4) AT1G80340(GA3OX2) AT4G21690(GA3OX3)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
101219147(GA3ox3) 101219385 101219623 101222387(GA3ox4) 101222627(GA3ox2) 101223012(Cs3OH1)
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0001s17680g(POPTRDRAFT_548646) POPTR_0003s05610g(POPTRDRAFT_756811) POPTR_0006s26380g POPTR_0018s01170g(POPTRDRAFT_578149)
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
DOSA: 
Os01t0177400-01(Os01g0177400) Os05t0178100-01(Os05g0178100)
BDI: 
SBI: 
SORBI_03g004020(SORBIDRAFT_03g004020) SORBI_09g005400(SORBIDRAFT_09g005400)
ZMA: 
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
 » show all
Taxonomy
Reference
1
  Authors
Kwak, S.-S., Kamiya, Y., Sakurai, A., Takahishi, N. and Graebe, J.E.
  Title
Partial-purification and characterization of gibberellin 3beta-hydroxylase from immature seeds of Phaseolus vulgaris L.
  Journal
Plant Cell Physiol. 29 (1988) 935-943.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
120860-89-1

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