EC               Enzyme                                 

benzoate 1,2-dioxygenase;
benzoate hydroxylase;
benzoate hydroxylase;
benzoic hydroxylase;
benzoate dioxygenase;
benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating) [incorrect]
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
BRITE hierarchy
benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)
benzoate + NADH + H+ + O2 = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ [RN:R07188]
benzoate [CPD:C00180];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate [CPD:C06321];
NAD+ [CPD:C00003]
A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), and an iron-sulfur oxygenase. Requires Fe2+.
EC created 1972 as EC, transferred 1992 to EC
ec00362  Benzoate degradation
ec00364  Fluorobenzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
K05549  benzoate/toluate 1,2-dioxygenase subunit alpha
K05550  benzoate/toluate 1,2-dioxygenase subunit beta
EFE: EFER_1482(benA) EFER_1483(benB)
KPN: KPN_01871 KPN_01872
KPU: KP1_2936(hcaF) KP1_2937(hcaE)
KPM: KPHS_28410 KPHS_28420
KPP: A79E_2373 A79E_2374
KPK: A593_24220 A593_24225
KPH: KPNIH24_14195 KPNIH24_14200
KPZ: KPNIH27_13580 KPNIH27_13585
KPV: KPNIH29_14250 KPNIH29_14255
KPW: KPNIH30_14515 KPNIH30_14520
KPT: VK055_0611(cbdA) VK055_0612(benB)
KPE: KPK_2484(cbeA) KPK_2485(cbeB)
KPR: KPR_2935(benB) KPR_2937
KPX: PMK1_04212(cbdB) PMK1_04213(cbdA_2)
KPNK: BN49_2971(benB) BN49_2972(benA)
PAE: PA2083 PA2517(xylY) PA2518(xylX)
PAEV: N297_2588(benB) N297_2589(benA)
PAEI: N296_2588(benB) N296_2589(benA)
PAU: PA14_32080(xylX) PA14_32100(xylY) PA14_37570
PAP: PSPA7_2719(benA) PSPA7_2720(benB)
PAG: PLES_27771(xylX) PLES_27781(xylY) PLES_32381
PAF: PAM18_2521(xylX) PAM18_2522(xylY)
PNC: NCGM2_3522(xylY) NCGM2_3523(xylX)
PAEB: NCGM1900_4009(xylX) NCGM1900_4010(xylY)
PAEU: BN889_02741(xylY) BN889_02742(xylX)
PAEC: M802_2585(benB) M802_2586(benA)
PAEO: M801_2453(benB) M801_2454(benA)
PRE: PCA10_30930(benB) PCA10_30940(benA)
PCQ: PcP3B5_23330(cbdA) PcP3B5_23340(cbdB)
PPU: PP_3161(benA) PP_3162(benB)
PPX: T1E_1062(benB) T1E_1063(benA)
PPUN: PP4_25370(benA) PP4_25380(benB) PP4_48200(benB) PP4_48210(benA)
PFL: PFL_3857(xylY) PFL_3858(xylX)
PPRC: PFLCHA0_c39150(xylY2) PFLCHA0_c39160(xylX2)
PPRO: PPC_3953(xylYI) PPC_3954
PFE: PSF113_2896(benB) PSF113_2897(benA)
PEN: PSEEN3142(benB) PSEEN3143(benA)
PSA: PST_1667(benA) PST_1668(benB)
PSZ: PSTAB_1578(benA) PSTAB_1579(benB)
PSR: PSTAA_1695(benA) PSTAA_1696(benB)
PPUU: PputUW4_03256(benB) PputUW4_03257(benA)
PSV: PVLB_12215(benA) PVLB_12220(benB)
PKC: PKB_2100(xylX) PKB_2101(xylY)
PSES: PSCI_4808(xylYI) PSCI_4809
PSOS: POS17_3978(xylYI) POS17_3979
AVN: Avin_08590(benA) Avin_08600(benB)
AVL: AvCA_08590(benA) AvCA_08600(benB)
AVD: AvCA6_08590(benA) AvCA6_08600(benB)
ACX: Achr_32830(benB) Achr_32840(benA)
ABM: ABSDF1497(benA)
ABY: ABAYE2555(benA) ABAYE2556(benB)
ABB: ABBFA_002364(benA) ABBFA_002365(benB)
ABAD: ABD1_12230(benB) ABD1_12240(benA)
ACC: BDGL_000465(benB) BDGL_000466(benA)
ACI: ACIAD1436(benA) ACIAD1437(benB)
ASJ: AsACE_CH01474(benA) AsACE_CH01475(benB)
AID: CTZ23_07110(benB) CTZ23_07115(benA)
MHC: MARHY0278 MARHY0279(benB)
MAD: HP15_1106
PSE: NH8B_1750(benA) NH8B_1751(benB)
RSC: RCFBP_11861(benB) RCFBP_11862(benA)
RSL: RPSI07_1886(benB) RPSI07_1887(benA)
REH: H16_A1962(benB) H16_A1963(benA)
CNC: CNE_1c19320(benB) CNE_1c19330(benA)
RME: Rmet_4882(benA) Rmet_4883(benB)
CUH: BJN34_08560(benA) BJN34_08565(benB)
BMA: BMAA0186(benB) BMAA0187(benA)
BMV: BMASAVP1_1359(benB) BMASAVP1_1360(benA)
BML: BMA10229_1554(benB) BMA10229_1555(benA)
BMN: BMA10247_A0214(benB) BMA10247_A0215(benA)
BMAL: DM55_3531(benA) DM55_3532(benB)
BMAE: DM78_4625(benB) DM78_4626(benA)
BMAQ: DM76_4228(benA) DM76_4229(benB)
BMAF: DM51_3937(benB) DM51_3938(benA)
BMAZ: BM44_3493(benA) BM44_3494(benB)
BMAB: BM45_4329(benA) BM45_4330(benB)
BPS: BPSS1903(benA) BPSS1904(benB)
BPM: BURPS1710b_A1000(benB)
BPD: BURPS668_A2725(benA) BURPS668_A2726(benB)
BPSE: BDL_5309(benA) BDL_5310(benB)
BPSM: BBQ_4226(benB) BBQ_4227(benA)
BPSU: BBN_5368(benA) BBN_5369(benB)
BPSD: BBX_4474(benA) BBX_4475(benB)
BPZ: BP1026B_II2042(benB) BP1026B_II2043(benA)
BPK: BBK_4642(benA) BBK_4643(benB)
BPSH: DR55_5830(benB) DR55_5831(benA)
BPSA: BBU_4105(benB) BBU_4106(benA)
BPSO: X996_5628(benB) X996_5629(benA)
BUT: X994_5191(benB) X994_5192(benA)
BTQ: BTQ_3765(benB) BTQ_3766(benA)
BTJ: BTJ_4796(benB) BTJ_4797(benA)
BTZ: BTL_5582(benB) BTL_5583(benA)
BTD: BTI_5086(benB) BTI_5087(benA)
BTV: BTHA_4618(benA) BTHA_4619(benB)
BTHE: BTN_5253(benB) BTN_5254(benA)
BTHM: BTRA_5523(benB) BTRA_5524(benA)
BTHL: BG87_5598(benB) BG87_5599(benA)
BOK: DM82_6193(benA) DM82_6194(benB)
BOC: BG90_4470(benB) BG90_4471(benA)
BVE: AK36_5308 AK36_5309(benB)
BCJ: BCAS0495(benB) BCAS0496(benA)
BCEN: DM39_5091(cbdA) DM39_5092(benB)
BCEW: DM40_5134(benB) DM40_5135(cbdA)
BCEO: I35_7539(benB) I35_7540(benA)
BMK: DM80_4617(cbdA) DM80_4618(benB)
BMUL: NP80_3315(benB) NP80_3316
BCED: DM42_7059(benB) DM42_7060(cbdA)
BDL: AK34_5717(benB) AK34_5718(cbdA)
BUB: BW23_4427(benB) BW23_4428(benA)
BGO: BM43_5500(benB) BM43_5501(cbdA)
BUL: BW21_4621(benB) BW21_4622(benA)
BXE: Bxe_B0914(benB) Bxe_B0915(benA)
BXB: DR64_6235(benB) DR64_6236(benA)
BPT: Bpet1398(benB) Bpet1399(benA)
ACRA: BSY15_1218(benB) BSY15_1219
HSE: Hsero_1308(cbeA) Hsero_1309(cbeB)
HRB: Hrubri_1093(cbeA2) Hrubri_1094(cbeB2) Hrubri_1134(cbeA) Hrubri_1135(cbeB)
SFD: USDA257_c54440(xylY) USDA257_c54450(cbdA)
BOS: BSY19_2043(benB) BSY19_2044(benA)
PZH: CX676_12375(benA) CX676_12380(benB)
SPHP: LH20_19245
SPHR: BSY17_106(benB) BSY17_107
AZL: AZL_a07340(benA) AZL_a07350(benB)
CGL: NCgl2320(Cgl2404) NCgl2321(Cgl2405)
CGB: cg2637(benA) cg2638(benB)
CGU: WA5_2320(BenA) WA5_2321(BenB)
CGM: cgp_2637(benA) cgp_2638
CMQ: B840_09740(benA) B840_09745(xylY)
RHA: RHA1_ro02384(benA) RHA1_ro02385(benB)
ROP: ROP_20980(benA) ROP_20990(benB)
RRZ: CS378_14015(benA) CS378_14020(benB)
RHU: A3Q40_00992(cbdA) A3Q40_00993(cbdB)
RQI: C1M55_27395(benA) C1M55_27400(benB)
GPO: GPOL_c38890(benA) GPOL_c38900(benB)
GOC: CXX93_01335(benA)
ARN: CGK93_10495(benA) CGK93_10500(benB)
SEN: SACE_4378(benB) SACE_4379(benA)
AMQ: AMETH_2178(benA) AMETH_2179(benB)
AMYC: CU254_24145(benB) CU254_24150(benA)
PDX: Psed_4287
PSEA: WY02_09515
 » show all
1  [PMID:214433]
Yamaguchi M, Fujisawa H.
Characterization of NADH-cytochrome c reductase, a component of benzoate 1,2-dioxygenase system from Pseudomonas arvilla c-1.
J. Biol. Chem. 253 (1978) 8848-53.
2  [PMID:7372624]
Yamaguchi M, Fujisawa H.
Purification and characterization of an oxygenase component in benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1.
J. Biol. Chem. 255 (1980) 5058-63.
3  [PMID:7130163]
Yamaguchi M, Fujisawa H.
Subunit structure of oxygenase component in benzoate-1,2-dioxygenase system from Pseudomonas arvilla C-1.
J. Biol. Chem. 257 (1982) 12497-502.
Other DBs
ExplorEnz - The Enzyme Database:
IUBMB Enzyme Nomenclature:
ExPASy - ENZYME nomenclature database:
UM-BBD (Biocatalysis/Biodegradation Database):
BRENDA, the Enzyme Database:
CAS: 9059-18-1

DBGET integrated database retrieval system