KEGG   ENZYME: 1.14.12.14Help
Entry
EC 1.14.12.14               Enzyme                                 

Name
2-aminobenzenesulfonate 2,3-dioxygenase;
2-aminosulfobenzene 2,3-dioxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
BRITE hierarchy
Sysname
2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)
Reaction(IUBMB)
2-aminobenzenesulfonate + NADH + H+ + O2 = 2,3-dihydroxybenzenesulfonate + NH3 + NAD+ [RN:R05156]
Reaction(KEGG)
Substrate
2-aminobenzenesulfonate [CPD:C06333];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
2,3-dihydroxybenzenesulfonate [CPD:C06336];
NH3 [CPD:C00014];
NAD+ [CPD:C00003]
Pathway
Benzoate degradation
Microbial metabolism in diverse environments
Orthology
K15766  
2-aminobenzenesulfonate 2,3-dioxygenase subunit alpha
K15767  
2-aminobenzenesulfonate 2,3-dioxygenase subunit beta
Reference
1  [PMID:8002948]
  Authors
Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM.
  Title
Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid.
  Journal
Biochem. J. 300 ( Pt 2) (1994) 429-36.
  Organism
Alcaligenes sp.
Reference
2  [PMID:8075807]
  Authors
Junker F, Leisinger T, Cook AM.
  Title
3-Sulphocatechol 2,3-dioxygenase and other dioxygenases (EC 1.13.11.2 and EC 1.14.12.-) in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. strain O-1.
  Journal
Microbiology. 140 ( Pt 7) (1994) 1713-22.
  Organism
Alcaligenes sp.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
156621-16-8

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