| Entry |
|
|---|
| Name |
4-sulfobenzoate 3,4-dioxygenase;
4-sulfobenzoate dioxygenase;
4-sulfobenzoate 3,4-dioxygenase system |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of two atoms of
oxygen into the other donor
 |
|---|
| Sysname |
4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating,
sulfite-forming) |
|---|
| Reaction(IUBMB) |
4-sulfobenzoate + NADH + H+ + O2 = 3,4-dihydroxybenzoate + sulfite +
NAD+ [RN:R01636] |
|---|
| Reaction(KEGG) |
R01636
 |
|---|
| Substrate |
4-sulfobenzoate [CPD:C02236];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007] |
|---|
| Product |
3,4-dihydroxybenzoate [CPD:C00230];
sulfite [CPD:C00094];
NAD+ [CPD:C00003] |
|---|
| Cofactor |
Iron [CPD:C00023];
FMN [CPD:C00061];
Iron-sulfur [CPD:C00824] |
|---|
| Comment |
A system, containing a reductase which is an iron-sulfur
flavoprotein (FMN), an iron-sulfur oxygenase, and no independent
ferredoxin. Requires Fe2+. |
|---|
| Pathway |
PATH: ec00623 2,4-Dichlorobenzoate degradation |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:2012609]
Locher HH, Leisinger T, Cook AM.
4-Sulphobenzoate 3,4-dioxygenase. Purification and properties of a
desulphonative two-component enzyme system from Comamonas
testosteroni T-2.
Biochem. J. 274 ( Pt 3) (1991) 833-42.
Comamonas testosteroni |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.12.8
IUBMB Enzyme Nomenclature: 1.14.12.8
ExPASy - ENZYME nomenclature database: 1.14.12.8
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.12.8
BRENDA, the Enzyme Database: 1.14.12.8
CAS: 122933-81-7 |
|---|
