KEGG   ENZYME: 1.14.13.107Help
Entry
EC 1.14.13.107              Enzyme                                 

Name
limonene 1,2-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
limonene,NAD(P)H:oxygen oxidoreductase
Reaction(IUBMB)
(1) (S)-limonene + NAD(P)H + H+ + O2 = 1,2-epoxymenth-8-ene + NAD(P)+ + H2O [RN:R09385 R09389];
(2) (R)-limonene + NAD(P)H + H+ + O2 = 1,2-epoxymenth-8-ene + NAD(P)+ + H2O [RN:R06398 R09393]
Reaction(KEGG)
Substrate
(S)-limonene;
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007];
(R)-limonene
Product
1,2-epoxymenth-8-ene;
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
A flavoprotein (FAD). Limonene is the most widespread terpene and is formed by more than 300 plants. Rhodococcus erythropolis DCL14, a Gram-positive bacterium, is able to grow on both (S)-limonene and (R)-limonene as the sole source of carbon and energy. NADPH can act instead of NADH, although more slowly. It has not been established if the product formed is optically pure or a mixture of two enantiomers.
History
EC 1.14.13.107 created 2009
Pathway
Limonene and pinene degradation
Orthology
K14733  
limonene 1,2-monooxygenase
Genes
MES: 
PLA: 
BJA: 
BJU: 
BJP: 
BRA: 
BBT: 
BRS: 
AOL: 
BRC: 
BRAD: 
PZU: 
RDE: 
RLI: 
SPHM: 
SSY: 
MTU: 
MTV: 
MTC: 
MRA: 
MTF: 
MTB: 
MTK: 
MTZ: 
MTG: 
MTI: 
MTE: 
MTUR: 
MTL: 
MTO: 
MTD: 
MTN: 
MTJ: 
MTUB: 
MTUC: 
MTUE: 
MTX: 
MTUL: 
MTUT: 
MTUU: 
MTQ: 
MCE: 
MCQ: 
MCV: 
MCX: 
MCZ: 
MPA: 
MAO: 
MAVI: 
MAVU: 
MAV: 
MAVD: 
MAVR: 
MAVA: 
MIT: 
MIR: 
MIA: 
MIE: 
MID: 
MYO: 
MSM: 
MSG: 
MSB: 
MSN: 
MSH: 
MSA: 
MUL: 
MVA: 
MGI: 
MSP: 
MAB: 
MABB: 
MMV: 
MAY: 
MABO: 
MABL: 
MAZ: 
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MKM: 
MJL: 
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MRH: 
MMM: 
MCB: 
MLI: 
MKN: 
MKS: 
MKI: 
MNE: 
MYV: 
MYE: 
MGO: 
MFT: 
MHAD: 
MPHL: 
MVQ: 
NCY: 
RHA: 
RER: 
REY: 
REB: 
ROP: 
ROP_46710(limB)
REQ: 
RAV: 
GPO: 
SCO: 
SCP1.240c(mmyO)
SCT: 
SCAT_0119(limB)
SCY: 
SBH: 
SHY: 
SHO: 
SALS: 
SRC: 
SALU: 
NAL: 
B005_2518(limB)
GOB: 
BSD: 
BLASA_2848(limB) BLASA_3512(limB2)
MMAR: 
ALU: 
PDX: 
PSEA: 
PSEE: 
PSEH: 
PSEQ: 
PECQ: 
SESP: 
BN6_21310(limB)
AYM: 
ABAI: 
 » show all
Taxonomy
Reference
1  [PMID:10224006]
  Authors
van der Werf MJ, Swarts HJ, de Bont JA.
  Title
Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene.
  Journal
Appl. Environ. Microbiol. 65 (1999) 2092-102.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 

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