KEGG   ENZYME: 1.14.13.153Help
Entry
EC 1.14.13.153              Enzyme                                 

Name
(+)-sabinene 3-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
(+)-sabinene,NADPH:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
(+)-sabinene + NADPH + H+ + O2 = (+)-cis-sabinol + NADP+ + H2O [RN:R09935]
Reaction(KEGG)
Substrate
(+)-sabinene [CPD:C20230];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
(+)-cis-sabinol [CPD:C02213];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Requires cytochrome P-450. The enzyme has been characterized from Salvia officinalis (sage).
History
EC 1.14.13.153 created 2012
Reference
1  [PMID:3111374]
  Authors
Karp F, Harris JL, Croteau R
  Title
Metabolism of monoterpenes: demonstration of the hydroxylation of (+)-sabinene to (+)-cis-sabinol by an enzyme preparation from sage (Salvia officinalis) leaves.
  Journal
Arch. Biochem. Biophys. 256 (1987) 179-93.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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