KEGG   ENZYME: 1.14.13.16Help
Entry
EC 1.14.13.16               Enzyme                                 

Name
cyclopentanone monooxygenase;
cyclopentanone oxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing)
Reaction(IUBMB)
cyclopentanone + NADPH + H+ + O2 = 5-valerolactone + NADP+ + H2O [RN:R02554]
Reaction(KEGG)
Substrate
cyclopentanone [CPD:C00557];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
5-valerolactone [CPD:C02240];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
History
EC 1.14.13.16 created 1976
Reference
1  [PMID:4349113]
  Authors
Griffin M, Trudgill PW.
  Title
The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872.
  Journal
Biochem. J. 129 (1972) 595-603.
Reference
2  [PMID:4313]
  Authors
Griffin M, Trudgill PW.
  Title
Purification and properties of cyclopentanone oxygenase of Pseudomonas NCIB 9872.
  Journal
Eur. J. Biochem. 63 (1976) 199-209.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37364-15-1

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