Entry |
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Name |
ent-sandaracopimaradiene 3-hydroxylase;
CYP701A;
OsKOL4
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Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
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Sysname |
ent-sandaracopimaradiene,NADPH:oxygen oxidoreductase (ent-sandaracopimaradien-3beta-ol forming)
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Reaction(IUBMB) |
ent-sandaracopimaradiene + NADPH + H+ + O2 = ent-sandaracopimaradien-3beta-ol + NADP+ + H2O [RN: R11656]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
A heme-thiolate protein (cytochrome P-450). Isolated from Oryza sativa (rice). Participates in the pathway for the biosynthesis of oryzalexins, a group of related phytoalexins produced by rice.
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History |
EC 1.14.13.191 created 2014
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Orthology |
| ent-sandaracopimaradiene 3-hydroxylase |
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Genes |
 |
Reference |
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Authors |
Wang Q, Hillwig ML, Wu Y, Peters RJ |
Title |
CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism. |
Journal |
Plant. Physiol. 158 (2012) 1418-25. |
Sequence |
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Reference |
|
Authors |
Wu Y, Wang Q, Hillwig ML, Peters RJ |
Title |
Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis. |
Journal |
Biochem. J. 454 (2013) 209-16. |
Sequence |
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Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: |