KEGG   ENZYME: 1.14.13.29Help
Entry
EC 1.14.13.29               Enzyme                                 

Name
4-nitrophenol 2-monooxygenase;
4-nitrophenol hydroxylase;
4-nitrophenol-2-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)
Reaction(IUBMB)
4-nitrophenol + NADH + H+ + O2 = 4-nitrocatechol + NAD+ + H2O [RN:R03023]
Reaction(KEGG)
Substrate
4-nitrophenol [CPD:C00870];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
4-nitrocatechol [CPD:C02235];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Comment
A flavoprotein (FAD).
History
EC 1.14.13.29 created 1989
Pathway
Aminobenzoate degradation
Microbial metabolism in diverse environments
Reference
1  [PMID:6477623]
  Authors
Mitra D, Vaidyanathan CS.
  Title
A new 4-nitrophenol 2-hydroxylase from a Nocardia sp.
  Journal
Biochem. Int. 8 (1984) 609-15.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
91116-87-9

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